Anemia After Partial Gastrectomy: Causes and Solutions - Internal Medicine

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Anemia


Twelve years ago, I underwent surgery for a gastric perforation (it seems to be referred to as a subtotal gastrectomy), where 2/3 of my stomach (the lower part) was removed.
The doctor mentioned that this would affect folate absorption.
I frequently experience anemia, and my hemoglobin levels have dropped as low as 4.6.
After taking iron supplements for nearly two years, my levels have improved to over 11, but if I stop taking the iron supplements, my hemoglobin levels decrease again.
I would like to know: 1.
Is this simply anemia? 2.
Are there any long-term side effects of taking iron supplements? 3.
Besides taking iron supplements, are there any better methods?

ivy, 30~39 year old female. Ask Date: 2000/11/14

Dr. Zeng Fenyu reply Internal Medicine


Hello Ivy: The most common type of anemia following gastric resection surgery is iron deficiency anemia, while anemia due to vitamin B12 deficiency or poor folate absorption is relatively rare.
Have you been taking iron supplements daily for the past two years? What is the dosage? Without detailed information, it is difficult for us to provide a response.
Generally, iron supplements should be taken for about 6-8 months to replenish the iron stores in the bone marrow.
The reason your hemoglobin drops when you stop taking iron supplements could be due to two factors: 1.
Your iron stores in the bone marrow have not been fully replenished, or 2.
There is bleeding somewhere in your body.
There is no better method than taking iron supplements, but if your iron levels are sufficient, you should not continue taking them, as this could lead to iron overload.
If you still have concerns regarding this issue, please consult a physician at the hospital for an evaluation of your current condition.
Hematology-Oncology Dr.
Peng Wen-Jie.

Reply Date: 2000/11/14

More Info


Anemia following partial gastrectomy, particularly after a significant resection like a subtotal gastrectomy, is a common complication that can arise due to several factors. Understanding the underlying causes and exploring potential solutions is crucial for managing this condition effectively.

1. Is this simply anemia?
The anemia you are experiencing is likely multifactorial. After a partial gastrectomy, the stomach's ability to produce intrinsic factor, which is essential for vitamin B12 absorption, may be compromised. This can lead to pernicious anemia, a type of macrocytic anemia caused by vitamin B12 deficiency. Additionally, the reduced surface area of the stomach can impair the absorption of iron and other nutrients, leading to iron deficiency anemia. Given your history of a hemoglobin level dropping to 4.6, it is essential to consider both iron deficiency and potential vitamin B12 deficiency as contributing factors to your anemia.

2. Are there long-term side effects of taking iron supplements?
Long-term use of iron supplements can have side effects, including gastrointestinal issues such as constipation, diarrhea, nausea, and abdominal discomfort. In some cases, excessive iron intake can lead to iron overload, which can damage organs such as the liver and heart. Therefore, it is crucial to monitor your iron levels regularly through blood tests to avoid potential toxicity. While iron supplements can be beneficial, they should be taken under medical supervision, especially for extended periods.

3. Are there better methods besides taking iron supplements?
In addition to iron supplementation, addressing the underlying causes of your anemia is vital. Here are some strategies that may help:
- Dietary Adjustments: Incorporate iron-rich foods into your diet, such as red meat, poultry, fish, lentils, beans, and fortified cereals. Pairing these foods with vitamin C-rich items (like citrus fruits, tomatoes, and bell peppers) can enhance iron absorption.

- Vitamin B12 and Folate: Since you mentioned that your doctor indicated potential issues with folate absorption, consider incorporating foods high in folate (such as leafy greens, legumes, and fortified grains) into your diet. Additionally, if vitamin B12 deficiency is suspected, you may need to consider B12 injections or high-dose oral supplements, as absorption can be significantly impaired post-surgery.

- Regular Monitoring: Regular follow-up with your healthcare provider is essential. They may recommend periodic blood tests to monitor your hemoglobin, ferritin, vitamin B12, and folate levels. This will help tailor your treatment plan effectively.

- Consult a Specialist: If your anemia persists despite dietary changes and supplementation, consider consulting a hematologist or a gastroenterologist. They can provide further evaluation and management options, including potential treatments for any underlying gastrointestinal issues that may be affecting nutrient absorption.

In summary, your anemia is likely not a simple case but rather a complex interplay of factors related to your partial gastrectomy. While iron supplements are a common treatment, they should be part of a broader strategy that includes dietary modifications and regular monitoring. Always consult with your healthcare provider before making any changes to your treatment plan to ensure that it is safe and appropriate for your specific situation.

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