Effective Strategies for Reducing Morphine Use After Tumor Surgery - Oncology

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Tapering method for morphine?


Hello Doctor,
Purpose: To reduce the dosage of morphine.

Original Situation: Prior to surgery, the patient experienced severe pain due to a tumor, leading to a total of 21 days of morphine use before and after the operation.
During hospitalization, medication was administered by the hospital, and at home, the patient took 30 mg of morphine every 12 hours.
The patient experienced side effects such as sleep talking and hand movements while asleep, and occasional tremors during wakefulness (which appeared as if the patient was being shocked).
The tumor was surgically removed on April 8, 2016, and the stitches have since been removed.
The patient hopes to decrease the use of pain medication.
Current Situation: The patient is currently taking a combination of hydromorphone and gastric medication every 12 hours, and APO every 6 hours.
However, the patient is experiencing a lack of appetite, inability to eat, night sweats, occasional chills, and intermittent tremors.
For instance, today the patient only consumed two-thirds of a medium cup of soy milk for breakfast and has not been able to eat anything else.
Question: The patient would like to confirm if adjustments to the pain medication can be made given the current situation, and if there are better ways to address the issues of lack of appetite, night sweats, occasional chills, and intermittent tremors.
Thank you very much.

Ms. Chen, 20~29 year old female. Ask Date: 2016/04/10

Dr. Chen Yunfang reply Oncology


Hello: The Celebrex you are currently taking is not morphine; it is simply a non-steroidal anti-inflammatory drug (NSAID) that is gentle on the stomach.
Are you sure you have taken morphine? If not, it is difficult to determine what these uncomfortable symptoms are related to.
Please discuss this with your primary physician! Thank you for your understanding.

Reply Date: 2016/04/10

More Info


Reducing morphine use after tumor surgery is a critical concern for many patients, especially those who have experienced significant pain prior to and following their surgical procedures. The transition from high doses of opioids to lower doses or alternative pain management strategies can be challenging, but there are effective strategies that can help manage pain while minimizing the side effects associated with opioid use.


Understanding the Current Situation
In your case, you have been using morphine for 21 days post-surgery, which is a common practice for managing acute postoperative pain. However, the side effects you are experiencing, such as vivid dreams, tremors, decreased appetite, and sweating, are not uncommon with opioid use. These symptoms can be exacerbated by the dosage and duration of morphine therapy. It is essential to address these side effects while effectively managing pain.


Strategies for Reducing Morphine Use
1. Gradual Tapering: Instead of abruptly stopping morphine, which can lead to withdrawal symptoms and increased pain perception, a gradual tapering schedule is recommended. This involves slowly reducing the dose over time, allowing your body to adjust to lower levels of the medication. Consult with your healthcare provider to create a tapering plan that suits your needs.

2. Multimodal Pain Management: Incorporating a multimodal approach to pain management can significantly reduce the reliance on opioids. This may include:
- Non-opioid analgesics: Medications such as acetaminophen or NSAIDs (e.g., ibuprofen) can be effective in managing pain without the side effects associated with opioids.

- Adjuvant medications: Certain medications, such as gabapentin or pregabalin, can help manage nerve pain and may reduce the need for opioids.

- Topical analgesics: Creams or patches containing lidocaine or capsaicin can provide localized pain relief without systemic side effects.

3. Physical Therapy: Engaging in physical therapy can help improve mobility and reduce pain through guided exercises. Physical therapists can provide tailored programs that focus on strengthening and flexibility, which can alleviate discomfort and improve overall function.

4. Alternative Therapies: Consider exploring complementary therapies such as acupuncture, massage therapy, or mindfulness-based stress reduction. These approaches can help manage pain and improve your overall well-being without relying solely on medications.

5. Diet and Hydration: Since you mentioned a lack of appetite and difficulty eating, it is crucial to focus on nutrition and hydration. Small, frequent meals that are easy to digest may help. Staying hydrated is also essential, as dehydration can exacerbate symptoms like dizziness and fatigue.

6. Monitoring and Communication: Regular follow-up appointments with your healthcare provider are vital. They can monitor your pain levels, adjust your medication regimen, and address any side effects you may be experiencing. Open communication about your symptoms and concerns is key to finding the right balance in your pain management plan.


Conclusion
Reducing morphine use after tumor surgery is a process that requires careful planning and support. By implementing a multimodal pain management strategy, gradually tapering your opioid use, and incorporating alternative therapies, you can effectively manage your pain while minimizing side effects. Always consult with your healthcare provider before making any changes to your medication regimen, as they can provide personalized guidance based on your specific situation. Remember, the goal is to achieve a balance between effective pain relief and maintaining your quality of life.

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