Experiencing Tingling on Tongue After CURAM Use: What to Know - Pharmacology

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Tingling sensation on the surface of the tongue (CURAM)?


Hello, Pharmacist Liao: After experiencing symptoms of sinusitis, I was prescribed CURAM and BAKTAR by my doctor.
After taking the medications for two days, I developed a tingling sensation on the surface of my tongue.
When I reported this to my doctor, they mentioned they had never heard of CURAM causing such an issue.
To investigate further, I observed myself during the next meal and noticed that the tingling sensation on my tongue reappeared when I took the medication again.
I am unsure what could be causing this.
Thank you very much!

RONG, 40~49 year old female. Ask Date: 2016/04/22

Dr. Liao Lingmei reply Pharmacology


Hello: The side effects of medications can vary from person to person.
Currently, there are no reports of tongue surface numbness associated with CURAM.
However, there are a few reports of peripheral neuropathy linked to BAKTAR.
Physicians typically evaluate whether to continue prescribing based on the premise that it does not affect the quality of life or cause unexpected harm, while still being able to treat the underlying condition.
Wishing you health and happiness!

Reply Date: 2016/04/22

More Info


Experiencing tingling on the tongue after taking CURAM (a combination of amoxicillin and clavulanate potassium) can be concerning and warrants further exploration. CURAM is commonly prescribed for various bacterial infections, including sinusitis, which you mentioned you were experiencing. The tingling sensation on your tongue could be attributed to several factors, and it’s essential to understand these to address your concerns adequately.

Firstly, it’s important to note that CURAM, like many antibiotics, can cause side effects. While tingling or numbness of the tongue is not commonly listed among the typical side effects of CURAM, it is not entirely unheard of. Some patients may experience oral side effects, including changes in taste, oral thrush (a fungal infection in the mouth), or even allergic reactions that could manifest as tingling or swelling in the oral cavity.
One possible explanation for the tingling sensation could be a mild allergic reaction to the medication. Allergic reactions can vary widely among individuals, and while some may experience more severe symptoms, others might have subtle reactions like tingling or a burning sensation in the mouth. If this tingling persists or worsens, it is crucial to consult your healthcare provider, as they may need to evaluate for a potential allergy or intolerance to the medication.

Another consideration is the impact of antibiotics on the oral microbiome. Antibiotics can disrupt the natural balance of bacteria in the mouth, potentially leading to an overgrowth of yeast, which can cause oral thrush. Symptoms of oral thrush can include a burning sensation and changes in taste, which might be perceived as tingling. If you suspect this might be the case, it would be advisable to discuss this with your doctor, who may recommend an antifungal treatment if necessary.

Additionally, the tingling sensation could be related to other factors unrelated to CURAM itself. For instance, dehydration, nutritional deficiencies (such as vitamin B12 or folate), or even anxiety can lead to sensations of tingling in the mouth. If you have been experiencing other symptoms, such as fatigue, changes in appetite, or mood changes, it may be worth discussing these with your healthcare provider to rule out other underlying conditions.

In terms of management, if the tingling sensation is mild and not accompanied by other concerning symptoms (such as swelling, difficulty breathing, or severe discomfort), you might consider monitoring the sensation for a few days. However, if it persists or if you develop additional symptoms, it would be prudent to return to your healthcare provider for further evaluation. They may consider switching your medication or conducting tests to determine the cause of your symptoms.

In conclusion, while tingling on the tongue after taking CURAM is not a widely recognized side effect, it can occur due to various reasons, including mild allergic reactions, disruption of the oral microbiome, or other unrelated factors. Close observation of your symptoms and communication with your healthcare provider will be key in addressing this issue effectively. Always prioritize your health and seek medical advice when experiencing unusual symptoms after medication use.

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