Is It Normal to Experience Headaches While Taking Escitalopram? - Pharmacology

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Escitalopram medication issues?


Hello, pharmacist.
I have been taking Escitalopram for two and a half months.
In the first couple of weeks, I experienced headaches, but those symptoms disappeared.
Recently, however, I have been experiencing headaches again (not very frequent, but sometimes I feel a sharp pain).
Is this normal? Thank you for taking the time to respond.

kid, 20~29 year old female. Ask Date: 2016/05/04

Dr. Huang Shenggang reply Pharmacology


Hello, thank you for your question.
According to the medication leaflet, 4% to 7% of individuals taking this medication may experience dizziness.

Reply Date: 2016/05/04

More Info


Experiencing headaches while taking Escitalopram, a selective serotonin reuptake inhibitor (SSRI) commonly prescribed for depression and anxiety, can be a concern for many patients. It is not uncommon for individuals to report headaches as a side effect when starting or adjusting their dosage of this medication.
Initially, during the first few weeks of treatment, some patients may experience a range of side effects, including headaches, nausea, fatigue, or dizziness. These symptoms often subside as the body adjusts to the medication. However, it is important to note that if headaches reoccur after a period of absence, as you described, it may warrant further investigation.

Headaches can be multifactorial, meaning they can arise from various causes. In the context of taking Escitalopram, it is essential to consider several factors:
1. Medication Side Effects: While headaches can be a side effect of Escitalopram, they are not universally experienced by all patients. If the headaches are mild and infrequent, they may be part of the adjustment process. However, if they become more frequent or severe, it is advisable to consult with your healthcare provider.

2. Tension Headaches: Given that you mentioned the headaches have a "stabbing" quality, they could also be tension-type headaches, which are common among individuals who experience stress or anxiety. If you are under stress or have been experiencing anxiety, this could contribute to tension headaches.

3. Other Factors: Consider other lifestyle factors that may contribute to your headaches. These can include dehydration, lack of sleep, poor posture (especially if you spend long hours at a computer), or even dietary factors. Keeping a headache diary can help identify potential triggers.

4. Withdrawal or Dosage Changes: If there have been any recent changes in your dosage or if you have missed doses, this could also lead to headaches. It is crucial to take medications as prescribed and to communicate any changes in your regimen with your healthcare provider.

5. Underlying Conditions: If headaches persist, it may be necessary to rule out other underlying conditions. This could include tension-type headaches, migraines, or even secondary headaches due to other medical issues. A thorough evaluation by a healthcare professional can help determine the cause.

In conclusion, while it is not unusual to experience headaches while taking Escitalopram, especially during the initial weeks of treatment, the recurrence of headaches after a period of absence should be discussed with your healthcare provider. They may recommend adjusting your dosage, switching medications, or exploring other potential causes for your headaches. It is essential to maintain open communication with your healthcare team to ensure that your treatment plan is effective and that any side effects are managed appropriately. Remember, your well-being is the priority, and addressing these concerns early can lead to better management of both your mental health and any associated symptoms like headaches.

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