Is Semen Reflux Normal After Stopping Ureteral Medication? - Urology

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Medication issues


I previously took Uroflow for urinary stones and have stopped the medication for about one day.
I am still experiencing retrograde ejaculation.
Is this normal?

A, 20~29 year old female. Ask Date: 2016/05/16

Dr. Chen Jiansheng reply Urology


Hello Mr.
A: The half-life of Urofollitropin is approximately 11 hours; however, it varies among individuals due to factors such as age, liver and kidney function, and body weight.
We should observe for a few more days, and this issue regarding drug elimination should resolve.
Best regards, Dr.
Chen Chien-Sheng, Urology Department, Hsin-Ying Hospital.

Reply Date: 2016/05/16

More Info


Semen reflux, or retrograde ejaculation, can indeed occur as a side effect of certain medications used to treat urinary tract conditions, including those like Urief (which contains the active ingredient solifenacin) and other similar drugs. These medications work by relaxing the bladder muscles and reducing urinary urgency and frequency, but they can also affect the normal function of the prostate and seminal vesicles, leading to retrograde ejaculation.

When you stop taking a medication that has caused retrograde ejaculation, it is not uncommon for the body to take some time to return to its normal function. In many cases, semen reflux can persist for a short period after discontinuation of the medication. This is because the physiological changes induced by the medication may not resolve immediately. Typically, most patients find that their ejaculation returns to normal within a few days to a couple of weeks after stopping the medication, but this can vary from person to person.

In your case, since you have only been off the medication for about one day, it is quite normal to still experience retrograde ejaculation. The body may need more time to adjust and restore normal ejaculatory function. If the condition persists beyond a couple of weeks or if you experience any other concerning symptoms, it would be advisable to consult your healthcare provider for further evaluation.

It's also important to note that while retrograde ejaculation is generally not harmful, it can be distressing for some individuals, particularly if they are trying to conceive. If you have concerns about fertility or if this condition is affecting your quality of life, discussing alternative treatment options with your doctor may be beneficial. There are various medications available for treating urinary issues that may not have the same side effects as Urief.

In summary, experiencing semen reflux after stopping ureteral medication is not unusual, especially shortly after discontinuation. It is advisable to monitor the situation and allow some time for your body to adjust. If symptoms persist or worsen, seeking medical advice is the best course of action.

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