Severe Acne: Causes, Treatments, and Recurrence Issues - Dermatology

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Painful and itchy, severely inflamed acne?


I started getting acne during puberty, initially not paying much attention to it.
However, it quickly escalated, starting from my forehead and spreading down to my cheeks and chin, covering my entire face.
The acne was large, red, and swollen.
I tried various medications, using everything available and switching from one doctor to another.
Some doctors eventually shook their heads in despair.
After ten years, there was some improvement, but after about a year of good days, my face began to break out with a large number of comedones again.
A friend recommended a beauty salon, and that’s when the nightmare began.
My face started to break out with more acne, and the instructor said it was a normal detox reaction.
As a result, I kept squeezing the emerging acne, and eventually, my entire face became red and swollen in areas where there were no pimples.
After taking anti-inflammatory medication for two weeks, there was still no improvement, and the acne remained severely inflamed.
Now, I go out wearing a mask, but even that is becoming ineffective.
Doctor, what should I do? Why do I keep experiencing relapses? Is it antibiotic resistance that is causing such severe inflammation during the treatment process? Sigh~~~~~~

Deng Dai Jiu Yuan, 20~29 year old female. Ask Date: 2002/09/11

Dr. Jiang Zheen reply Dermatology


Your issue is quite complex, and it would be best to consult a dermatologist for proper treatment.
If you live in the northern part of Taiwan, you can see Dr.
Chen Yan-Liang at National Taiwan University.
If you are in the southern part, you can visit the well-known acne specialist Dr.
Lin Bing-Huang in Tainan.
Wishing you good health.

Reply Date: 2002/09/11

More Info


Severe acne, often referred to as acne vulgaris, is a common skin condition that can significantly impact an individual's quality of life. It typically begins during puberty due to hormonal changes, but it can persist into adulthood. Understanding the causes, treatments, and issues related to recurrence is crucial for effective management.


Causes of Severe Acne
Acne develops when hair follicles become clogged with oil (sebum) and dead skin cells. Several factors contribute to this process:
1. Hormonal Changes: Androgens, which increase during puberty, can enlarge sebaceous glands and increase sebum production. This is often why teenagers experience acne.

2. Bacterial Growth: The presence of *Propionibacterium acnes*, a bacteria that thrives in clogged pores, can lead to inflammation and the formation of pustules and cysts.

3. Inflammation: The body’s immune response to bacteria and clogged pores can lead to redness, swelling, and pain associated with severe acne.

4. Genetics: A family history of acne can increase the likelihood of developing severe forms of the condition.

5. Diet and Lifestyle: Some studies suggest that high glycemic index foods and dairy products may exacerbate acne. Stress and lack of sleep can also contribute to flare-ups.


Treatments for Severe Acne
Managing severe acne often requires a multifaceted approach:
1. Topical Treatments: Over-the-counter products containing benzoyl peroxide or salicylic acid can help reduce mild to moderate acne. For severe cases, prescription topical retinoids (like tretinoin) and antibiotics may be necessary.

2. Oral Medications: Antibiotics (such as doxycycline or minocycline) can help reduce inflammation and bacterial growth. Hormonal treatments, such as oral contraceptives for women, can also be effective in regulating hormones that trigger acne.

3. Isotretinoin: For severe, treatment-resistant acne, isotretinoin (commonly known by the brand name Accutane) may be prescribed. This powerful medication can lead to significant improvement but requires careful monitoring due to potential side effects.

4. Procedural Treatments: Dermatological procedures such as chemical peels, laser therapy, and drainage of cysts can provide relief and improve skin appearance.

5. Lifestyle Modifications: Maintaining a consistent skincare routine, avoiding harsh scrubs, and using non-comedogenic products can help manage acne. Additionally, a balanced diet and stress management techniques may also be beneficial.


Recurrence Issues
Recurrence of acne can be frustrating and is often due to several factors:
1. Hormonal Fluctuations: Changes in hormone levels, particularly in women related to menstrual cycles, can trigger flare-ups.

2. Inadequate Treatment: If acne is not treated aggressively enough, it may return. It's essential to follow a comprehensive treatment plan tailored to the severity of the condition.

3. Skin Care Products: Some products can clog pores or irritate the skin, leading to new breakouts. It's crucial to choose appropriate skincare products.

4. Antibiotic Resistance: Overuse of topical or oral antibiotics can lead to resistance, making it harder to treat acne effectively. This may explain why some treatments seem to lose effectiveness over time.


Conclusion
If you are experiencing severe acne that has not responded to various treatments, it is advisable to consult a dermatologist who can provide a thorough evaluation and develop a personalized treatment plan. They can help identify any underlying issues contributing to your acne and adjust your treatment accordingly. Remember, managing severe acne is often a long-term process, and patience is key. Regular follow-ups and open communication with your healthcare provider can lead to better outcomes and improved skin health.

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