Managing Acid Reflux: Long-Term Effects of Medication and Dietary Tips - Gastroenterology and Hepatology

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Gastroesophageal reflux disease (GERD)


Hello, Dr.
Chen.
Last year, I was diagnosed with gastroesophageal reflux disease (GERD) after undergoing an endoscopy.
Sometimes when it flares up, I need to take medication.
Will long-term use of these medications have any effects on my body? I take acid-suppressing medication and sometimes take lutein, and I also take pain relievers for menstrual cramps.
Why do I experience symptoms of redness, swelling, and itching on my lips the next day, followed by skin breakdown and small blisters a few days later? Since starting the medication, my weight has been decreasing, and my body fat percentage is now too low.
What can I do to improve this situation? Should I also reduce my intake of overly salty foods?

Honglong Rong, 20~29 year old female. Ask Date: 2016/06/14

Dr. Chen Qifeng reply Gastroenterology and Hepatology


1.
It seems more likely to be a drug allergy.
2.
High salt intake may not necessarily affect gastroesophageal reflux, while excessive sweetness or acidity is more likely to have an impact.

Reply Date: 2016/06/14

More Info


Managing acid reflux can be a complex issue, especially when it involves long-term medication use and dietary considerations. Based on your situation, it seems you have been diagnosed with gastroesophageal reflux disease (GERD) and are taking medication to manage your symptoms. Let's break down your concerns regarding the long-term effects of medication, dietary tips, and the symptoms you are experiencing.


Long-Term Effects of Acid Reflux Medication
The medications commonly prescribed for acid reflux include proton pump inhibitors (PPIs) like omeprazole and lansoprazole, and H2 receptor antagonists like famotidine. While these medications are effective in reducing stomach acid and alleviating symptoms, long-term use can lead to several potential side effects:
1. Nutrient Absorption: Long-term use of PPIs can interfere with the absorption of certain nutrients, particularly vitamin B12, magnesium, and calcium. This can lead to deficiencies that may cause symptoms like fatigue, muscle cramps, or bone density loss.

2. Gastrointestinal Issues: Prolonged use of acid-reducing medications can alter the gut microbiome, potentially leading to an increased risk of gastrointestinal infections, such as Clostridium difficile.

3. Kidney Health: Some studies have suggested a link between long-term PPI use and an increased risk of chronic kidney disease.

4. Rebound Acid Hypersecretion: When stopping PPIs, some individuals may experience an increase in acid production, leading to a return of symptoms.


Dietary Tips for Managing Acid Reflux
Diet plays a crucial role in managing acid reflux symptoms. Here are some dietary tips that may help:
1. Avoid Trigger Foods: Common triggers include spicy foods, citrus fruits, tomatoes, chocolate, caffeine, and fatty or fried foods. Keeping a food diary can help identify your personal triggers.

2. Eat Smaller Meals: Large meals can increase pressure on the lower esophageal sphincter, leading to reflux. Eating smaller, more frequent meals can help.

3. Stay Upright After Eating: Remaining upright for at least two to three hours after meals can help prevent reflux.

4. Limit Alcohol and Caffeine: Both can relax the lower esophageal sphincter and exacerbate symptoms.

5. Reduce Sodium Intake: High-sodium foods can lead to water retention and may exacerbate symptoms. Opt for fresh foods and limit processed foods that are often high in salt.


Addressing Your Symptoms
You mentioned experiencing red, swollen, itchy lips and the development of small blisters. These symptoms could be related to several factors:
- Allergic Reaction: It’s possible that you are experiencing an allergic reaction to one of the medications you are taking, or even to dietary components. Consider discussing this with your healthcare provider.

- Medication Side Effects: Some medications can cause skin reactions. If you suspect this is the case, consult your doctor for alternatives.

- Dehydration or Nutritional Deficiencies: Given your weight loss and low body fat, you may be experiencing dehydration or deficiencies that could affect your skin health.


Weight Management
If you are losing weight unintentionally, it is essential to address this with your healthcare provider. They can help determine the underlying cause and suggest appropriate interventions. This may include dietary adjustments to ensure you are consuming enough calories and nutrients.


Conclusion
Managing acid reflux effectively requires a combination of medication, dietary changes, and monitoring for side effects. It is crucial to maintain open communication with your healthcare provider about your symptoms and any concerns regarding your medications. They can provide personalized advice and adjustments to your treatment plan as needed. Remember, lifestyle changes can significantly impact your symptoms and overall health, so consider integrating these dietary tips into your daily routine.

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