Can You Use Topical Treatments for Genital Warts After Surgery? - Urology

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Can medication be applied to condyloma acuminatum lesions?


Hello, I recently had a growth on the left side of my penile frenulum, which was surgically removed.
The pathology report confirmed it was a lesion of condyloma acuminatum (genital warts).
After four months of follow-up examinations, my doctor found no signs of recurrence.
However, during the three months following the surgery, I noticed that the skin on the right side of my frenulum was darker than my normal skin tone (unlike typical genital warts, this was just a subtle darkened area).
When I returned for a follow-up after four months, I requested surgical removal of that area, and the pathology again confirmed it was condyloma acuminatum.
Since my doctor assessed the situation differently from the pathology report, I have some questions:
Q1: If there is no visible condyloma acuminatum lesion, is it safe to use topical treatments like imiquimod or podophyllotoxin on the suspicious area? Could this cause irreversible damage to the skin or body?
Q2: After treatment for condyloma acuminatum with no signs of recurrence, and with my doctor also confirming no recurrence or reinfection, is it safe to engage in unprotected sexual intercourse?
Q3: Following up on Q2, if my doctor believes there is no recurrence or reinfection, and after one year, I have not had sexual intercourse with a new partner, I have advised them to receive three doses of the 9-valent HPV vaccine.
If we then engage in unprotected sexual intercourse, is there still a risk of transmitting the virus to my partner? What is the likelihood of transmission?

BUSA, 40~49 year old female. Ask Date: 2016/07/05

Dr. Chen Jiansheng reply Urology


Hello, Sir:
Q1: For warts (condylomata acuminata) lesions, is it safe to use wart treatments like Podophyllotoxin or Imiquimod on the suspicious areas? Will it cause irreversible damage to the body or skin?
A: Personally, I have not heard of any irreversible effects on the body.
Q2: If a person has been treated for warts (condylomata acuminata) and there has been no recurrence, and the physician also believes there is no recurrence or reinfection, is it safe to have unprotected sexual intercourse?
A: If it is confirmed that there is no recurrence, the risk of transmission is generally very low.
Q3: Following up on Q2, if the physician believes there is no recurrence or reinfection, and after one year, I have not had sexual intercourse with a new partner, I also asked him to receive three doses of the 9-valent HPV vaccine.
If we then engage in unprotected sexual intercourse, is there still a risk of him getting infected? What is the likelihood of transmission?
A: Based on current evidence, I cannot answer your question.

Reply Date: 2016/07/05

More Info


When it comes to managing genital warts, particularly after surgical removal, there are several important considerations to keep in mind regarding treatment, sexual activity, and the risk of recurrence or transmission.

Q1: Can I use topical treatments like wart removers on areas without visible warts?
Using topical treatments such as wart removers (e.g., imiquimod or podophyllin) on areas that do not have visible warts is generally not recommended without consulting a healthcare provider. These treatments are designed to target specific viral infections and can cause irritation or damage to healthy skin if applied indiscriminately. The skin in the genital area is sensitive, and using these products on non-infected skin could lead to adverse reactions, including inflammation, pain, or even scarring. Therefore, it is crucial to consult your doctor before applying any topical treatments to ensure they are appropriate for your specific situation.

Q2: After treatment for genital warts, can I engage in unprotected sexual intercourse if my doctor believes there is no recurrence or new infection?
While your doctor may assess that there is no visible recurrence of genital warts, it is essential to understand that the human papillomavirus (HPV), which causes genital warts, can remain dormant in the body. This means that even if you do not have visible symptoms, there is still a risk of transmitting the virus to a partner. Engaging in unprotected sexual intercourse carries the risk of transmission, especially if your partner has not been vaccinated against HPV. It is advisable to discuss with your healthcare provider about the timing and safety of resuming unprotected sexual activity.

Q3: If my partner has received the HPV vaccine, is there still a risk of transmission after I have been treated for genital warts?
The HPV vaccine is effective in preventing certain strains of the virus that cause genital warts and some types of cancer. If your partner has received the full series of the 9-valent HPV vaccine, their risk of contracting the strains covered by the vaccine is significantly reduced. However, it is important to note that the vaccine does not provide protection against all strains of HPV. If you have had a history of genital warts, there is still a potential risk of transmission, particularly if the strains involved are not covered by the vaccine. The likelihood of transmission can depend on various factors, including the presence of any active lesions, the immune status of both partners, and the specific strains of HPV involved.

In conclusion, while surgical removal of genital warts can be effective, ongoing vigilance is necessary. It is crucial to maintain open communication with your healthcare provider regarding any concerns about recurrence, the use of topical treatments, and safe sexual practices. Regular follow-ups and discussions about vaccination for partners can also help mitigate risks associated with HPV transmission. Always prioritize safe sex practices, including the use of condoms, to further reduce the risk of transmission, even when both partners are aware of their HPV status.

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