Impact of Chemotherapy and Abortion Medications on Pregnancy After Cancer - Obstetrics and Gynecology

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Medication issues


Doctor, I am currently in stage II of gastric cancer and have completed treatment with the chemotherapy drug Aiswan.
Since lymph nodes tested positive for metastasis, I need to continue medication.
Although all the lymph nodes have been removed, I am still concerned about the possibility of metastasis.
Unexpectedly, I am now pregnant and have been advised to terminate the pregnancy.
Will the abortion medication and chemotherapy drugs have any effects?

Xiao Lan, 30~39 year old female. Ask Date: 2016/07/10

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it is generally not recommended to conceive while undergoing chemotherapy.
If the gestational age is small, the option of using abortion medication can be considered.
Wishing you good health.

Reply Date: 2016/07/10

More Info


When it comes to the impact of chemotherapy and abortion medications on pregnancy, especially in the context of a cancer survivor, there are several important factors to consider. First and foremost, it is critical to understand the potential effects of chemotherapy drugs on both the mother and the developing fetus.
Chemotherapy agents, such as those used in the treatment of gastric cancer, can have teratogenic effects, meaning they can cause developmental abnormalities in a fetus. The risk of these effects largely depends on the specific drugs used, the timing of exposure during pregnancy, and the dosage. If chemotherapy was administered before conception, the risk to the fetus is generally lower, but if chemotherapy is ongoing during pregnancy, the risks can be significant.
For instance, certain chemotherapy drugs are known to cross the placenta and may affect fetal development, potentially leading to complications such as low birth weight, preterm birth, or congenital anomalies. Therefore, it is crucial to consult with both an oncologist and an obstetrician who specializes in high-risk pregnancies to assess the specific chemotherapy regimen and its implications for pregnancy.

Regarding abortion medications, the effects can vary depending on the type of medication used. Medications such as mifepristone and misoprostol, commonly used for medical abortions, can have side effects that may impact future pregnancies. However, if the decision is made to terminate the pregnancy, it is essential to follow medical guidance to ensure that the process is safe and minimizes any potential risks to the mother's health.

If you are considering an abortion while on chemotherapy, it is vital to discuss this with your healthcare providers. They can provide personalized advice based on your medical history, the specifics of your cancer treatment, and the current state of your health.
In summary, the impact of chemotherapy and abortion medications on pregnancy is complex and requires careful consideration. It is essential to have open and honest discussions with your healthcare team to make informed decisions that prioritize both your health and the potential health of the fetus. If you are feeling uncertain or anxious about your situation, seeking support from mental health professionals or support groups for cancer survivors may also be beneficial.

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