Mediastinal Tumors: Symptoms and Concerns for Your Health - Oncology

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Symptoms of mediastinal tumors may include: 1. Chest pain or discomfort 2. Coughing, which may be persistent or worsening 3. Shortness of breath or difficulty breathing 4. Wheezing or stridor (a high-pitched wheezing sound) 5. Hoarseness or changes in voice


My mother is 64 years old.
In 2013, a CT scan revealed a mass in the mediastinum measuring 7x4 cm.
A follow-up examination in 2014 showed no changes.
However, this year in 2016, an X-ray suggested that it may have increased in size, and a CT scan is being scheduled for confirmation.
My mother has issues with autonomic nervous system dysregulation, and since the beginning of this year, she has been experiencing significant chest weakness and dizziness.
I would like to ask the physician if the dizziness and chest weakness could possibly be due to the tumor enlarging and compressing blood vessels or other tissues.
Thank you.

Paul, 30~39 year old female. Ask Date: 2016/07/22

Dr. Hu Ziren reply Oncology


Hello, netizen: A mediastinal tumor may be a thymoma, which can be associated with myasthenia gravis.
This condition can affect the ocular muscles, leading to ptosis and diplopia; if it impacts the respiratory muscles, it may result in respiratory muscle weakness or respiratory failure.
A small portion may also be associated with pure red cell aplasia, causing anemia and dizziness.
Some patients experience symptom improvement after surgery, while others may require postoperative radiation therapy or chemotherapy.
By Dr.
Hu Zi-ren.

Reply Date: 2016/07/22

More Info


Understanding mediastinal tumors is crucial, especially when there are concerning symptoms and imaging findings. In your mother's case, the presence of a mediastinal mass that has been monitored over several years raises important questions about its nature and potential impact on her health.

Mediastinal tumors can arise from various tissues, including lymphatic, nerve, and connective tissues, and they can be benign or malignant. The symptoms associated with mediastinal tumors often depend on their size, location, and the structures they may be compressing. Common symptoms include chest pain, cough, shortness of breath, and systemic symptoms like weight loss or fever. In your mother's case, the symptoms of dizziness and chest weakness could indeed be related to the tumor's size and its effects on surrounding structures.

Given that the tumor was initially measured at 7x4 cm and has shown no significant change until recently, it is essential to consider the possibility that it may be growing or causing pressure effects. The mediastinum houses vital structures, including the heart, major blood vessels, trachea, and esophagus. If a tumor enlarges, it could potentially compress these structures, leading to symptoms such as:
1. Dizziness: This could occur if the tumor compresses blood vessels, particularly those supplying the brain, leading to reduced blood flow and resulting in dizziness or lightheadedness.

2. Chest Weakness: This symptom may arise from several factors, including anxiety related to her health concerns, the physical effects of the tumor on the chest wall or lungs, or even cardiac issues if the tumor is affecting the heart or major vessels.

3. Autonomic Nervous System Symptoms: Your mention of autonomic nervous system dysregulation could also play a role. Symptoms like dizziness and chest discomfort can be exacerbated by anxiety, stress, or other underlying conditions that may not be directly related to the tumor.

It is crucial to follow up with imaging studies, such as a CT scan, to assess the current status of the mediastinal mass. This will help determine if there has been any significant change in size or characteristics that might suggest malignancy or other complications. If the tumor is indeed growing, further evaluation, including a biopsy, may be necessary to ascertain its nature.

In summary, while the symptoms your mother is experiencing could potentially be related to the mediastinal tumor, they could also stem from other causes, including anxiety or other medical conditions. It is essential to have a thorough evaluation by her healthcare provider, including imaging studies and possibly further diagnostic procedures, to clarify the situation and guide appropriate management. Early detection and intervention are key in addressing any potential complications associated with mediastinal tumors.

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