Post-Inflammatory Eye Allergies and Treatment Options - Ophthalmology

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Allergic reaction after recovery from eye inflammation?


Hello, Doctor! I previously had conjunctivitis and keratitis, and now my conjunctiva is a bit allergic.
The ophthalmologist prescribed PATADAY® (olopatadine hydrochloride ophthalmic solution) 0.2%.
After using the antihistamine eye drops, my eyes become very red after washing my hair and taking a shower, with visible blood vessels extending to the cornea.
There is a blood vessel at the inner corner of my eye that remains red due to the previous inflammation, and this vessel extends red along the edge of the cornea, affecting about a quarter of the corneal margin.
After a while, all the red blood vessels dissipate.
I would like to ask the doctor: is this redness along the cornea harmful to my eyes? Additionally, I read online that during eye inflammation, inflammatory substances such as inflammatory cells can accumulate and obstruct the anterior chamber.
Will these inflammatory substances remain in the eye indefinitely, or will they eventually be cleared out? I hope the doctor can provide some answers.
Thank you!

carol, 30~39 year old female. Ask Date: 2016/08/24

Dr. Cai Wenyuan reply Ophthalmology


Transient inflammation should not cause harm.
Inflammatory cells obstructing the anterior chamber indicate intraocular inflammation, which is unrelated to conjunctivitis.
As the inflammation subsides, the inflammatory substances will naturally disappear.
Online responses can only serve as a reference; it is essential to seek medical attention at a healthcare facility if necessary.
Thank you.

Reply Date: 2016/08/24

More Info


Post-inflammatory eye allergies can be a frustrating and uncomfortable condition, especially after experiencing conjunctivitis and keratitis. It’s important to understand the underlying mechanisms of these allergies and the treatment options available to manage symptoms effectively.

When your eyes have been previously inflamed, such as from conjunctivitis or keratitis, they can become hypersensitive to allergens. This hypersensitivity can lead to allergic reactions, which manifest as redness, itching, and swelling. The redness you are experiencing, particularly the blood vessels extending to the cornea, is a common response to irritation or inflammation. The blood vessels dilate in response to inflammation, which can lead to the appearance of redness.
In your case, the use of PATADAY® (olopatadine hydrochloride ophthalmic solution) is appropriate as it is an antihistamine that helps alleviate allergic symptoms by blocking histamine receptors in the eyes. However, it’s crucial to monitor how your eyes respond to the medication and any other factors that may exacerbate your symptoms, such as washing your hair or taking a shower. The redness that appears after these activities may be due to the irritation from water, shampoo, or other products coming into contact with your eyes.

Regarding your concern about the blood vessels that extend to the corneal edge, while it can be alarming to see these changes, they are often a temporary response to inflammation. As the inflammation subsides, these blood vessels typically regress, and the redness should diminish. However, persistent redness or the development of new symptoms should be evaluated by your eye care provider to rule out any underlying issues.

As for the inflammatory substances produced during an eye infection, such as inflammatory cells and mediators, they are usually cleared from the eye over time. The body has mechanisms to resolve inflammation, and these substances are typically absorbed or eliminated through the lymphatic system or other pathways. However, if inflammation is chronic or severe, it can lead to complications, such as scarring or changes in the corneal structure, which may require further intervention.

To manage your symptoms effectively, consider the following recommendations:
1. Avoid Irritants: Minimize exposure to potential irritants, such as smoke, dust, and strong fragrances. Be cautious with hair products and ensure they do not come into contact with your eyes.

2. Use Artificial Tears: If your eyes feel dry or irritated, using preservative-free artificial tears can help lubricate the eyes and wash away allergens.

3. Follow Up with Your Eye Doctor: Regular follow-ups are essential to monitor your condition. If symptoms persist or worsen, your doctor may need to adjust your treatment plan.

4. Cold Compresses: Applying a cold compress to your closed eyes can help reduce redness and soothe irritation.

5. Avoid Rubbing Your Eyes: This can exacerbate irritation and lead to further inflammation.

6. Consider Environmental Controls: If you have known allergens, such as pollen or pet dander, consider measures to reduce exposure, like using air purifiers or keeping windows closed during high pollen seasons.

In summary, while the redness and inflammation you are experiencing can be concerning, they are often part of the healing process following an eye infection. With appropriate treatment and care, symptoms should improve over time. If you have any ongoing concerns or if your symptoms do not improve, it is essential to consult your eye care provider for further evaluation and management.

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