Elevated CA-125 Levels: Is It Ovarian Cancer? - Obstetrics and Gynecology

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Elevated CA-125 levels can indeed be concerning, especially when there is a suspicion of ovarian cancer. However, it is crucial to understand that CA-125 is not a definitive marker for ovarian cancer. It is a protein that is often elevated in women with ovarian cancer, but it can also be elevated in a variety of other conditions, both benign and malignant.
In your case, a CA-125 level of 105.6 is considered elevated, as the normal range is typically below 35 U/mL. However, this elevation does not automatically indicate the presence of ovarian cancer. Conditions such as endometriosis, pelvic inflammatory disease, fibroids, and even menstruation can cause an increase in CA-125 levels. Since you mentioned that you experience menstrual pain, it is possible that your elevated CA-125 could be related to your menstrual cycle or other benign gynecological conditions.

It is important to note that CA-125 is not specific to ovarian cancer. For instance, women with endometriosis often have elevated CA-125 levels, and this condition is not cancerous. Similarly, other benign conditions such as liver disease, kidney disease, and even certain cancers of the uterus or pancreas can also lead to increased CA-125 levels.

Given your elevated CA-125 level, it is advisable to follow up with your healthcare provider for further evaluation. This may include imaging studies such as ultrasound or CT scans to assess the ovaries and surrounding structures. A thorough evaluation by a gynecologist or oncologist is essential to determine the cause of the elevated CA-125 and to rule out any serious conditions.

In addition to imaging, your doctor may recommend monitoring your CA-125 levels over time. If the levels remain elevated or continue to rise, further investigation may be warranted, including possibly a biopsy or surgical intervention to obtain a definitive diagnosis.

In summary, while an elevated CA-125 level can be a marker of ovarian cancer, it is not a standalone diagnostic tool. It is essential to consider the full clinical picture, including symptoms, imaging results, and other laboratory findings. Regular follow-up and open communication with your healthcare provider are crucial in managing your health and addressing any concerns you may have. Remember, early detection and intervention are key in managing any potential health issues effectively.