Antibiotics: Managing Urological Infections Safely - Urology

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About antibiotics?


Hello doctor, I have a wound on the lower inner side of my right thigh.
I visited a general dermatology clinic where I was prescribed Cefuroxime (four times a day) and advised to see a larger hospital.
Later, after having the wound treated at the larger hospital, I was prescribed Noxafil (twice a day).
Should I stop taking Cefuroxime and switch to Noxafil? Will this cause any antibiotic resistance?

A-Shun, 30~39 year old female. Ask Date: 2016/09/08

Dr. Sun Hongshun reply Urology


Hello: The subsequent physician should advise you to discontinue the previous medication and take the prescribed medication instead.
Please follow the doctor's instructions carefully and do not stop the medication arbitrarily to avoid issues with drug resistance.
It is recommended to continue follow-up treatment at the outpatient clinic of a major hospital with that physician.

Reply Date: 2016/09/08

More Info


When it comes to managing urological infections and the use of antibiotics, it's essential to understand the implications of antibiotic resistance and the appropriate use of different antibiotics. In your case, you have been prescribed two different antibiotics: Cefuroxime (賜福力) and Norfloxacin (諾快寧).
First, let's clarify the role of these antibiotics. Cefuroxime is a second-generation cephalosporin antibiotic that is effective against a variety of bacteria, including some strains of Staphylococcus and Streptococcus, as well as certain Gram-negative bacteria. It is commonly used for skin infections, respiratory tract infections, and urinary tract infections. On the other hand, Norfloxacin is a fluoroquinolone antibiotic that is primarily used to treat urinary tract infections and some gastrointestinal infections. It works by inhibiting bacterial DNA synthesis, making it effective against a range of Gram-negative bacteria.

In terms of your treatment, if your healthcare provider at the hospital has prescribed Norfloxacin, it is likely because they believe it is more appropriate for your specific condition, especially considering the nature of your wound and any potential bacterial infection associated with it. It is generally advisable to follow the guidance of the healthcare provider who has assessed your condition more thoroughly.
Regarding the question of whether you should stop taking Cefuroxime to start Norfloxacin, this decision should ideally be made in consultation with your healthcare provider. If the hospital physician has recommended Norfloxacin, they may have determined that it is more suitable for your current situation. However, it is crucial to complete the course of any antibiotic unless advised otherwise by a healthcare professional, as stopping treatment prematurely can contribute to antibiotic resistance and may not fully resolve the infection.

Antibiotic resistance is a significant concern in modern medicine. It occurs when bacteria evolve and develop the ability to defeat the drugs designed to kill them. This can happen for several reasons, including the overuse and misuse of antibiotics. When antibiotics are used inappropriately, such as not completing a prescribed course or using them for viral infections, it can lead to the development of resistant strains of bacteria.
To mitigate the risk of developing antibiotic resistance, it is essential to use antibiotics judiciously. Here are some strategies to consider:
1. Complete the Course: Always complete the prescribed course of antibiotics, even if you start feeling better before finishing the medication. This ensures that all the bacteria are eliminated and reduces the chance of developing resistance.

2. Follow Medical Advice: Always consult your healthcare provider before making any changes to your medication regimen. They can provide guidance based on your specific medical history and the nature of your infection.

3. Avoid Self-Medication: Do not take antibiotics that were prescribed for someone else or use leftover antibiotics from previous treatments. Each infection may require a different antibiotic based on the bacteria involved.

4. Practice Good Hygiene: Maintaining good hygiene can help prevent infections and reduce the need for antibiotics. This includes regular handwashing, proper wound care, and avoiding close contact with individuals who are ill.

5. Stay Informed: Educate yourself about the appropriate use of antibiotics and the risks associated with antibiotic resistance. Understanding when antibiotics are necessary can help you make informed decisions about your health.

In summary, if you have been prescribed Norfloxacin after seeing a specialist, it is advisable to follow their recommendations. Discuss with your healthcare provider whether you should stop Cefuroxime and transition to Norfloxacin. By adhering to prescribed treatments and practicing good health habits, you can help combat antibiotic resistance and ensure effective management of your urological infection.

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