Gastrointestinal and Liver Health: When to Seek Further Testing - Gastroenterology and Hepatology

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Gastrointestinal, liver, and kidney?


Hello Doctor, I have been experiencing some discomfort in my stomach for the past two weeks.
It feels bloated and sometimes a bit painful.
I recently had a cold, and my doctor mentioned that it might be related to that.
However, I have noticed blood in my stool on two occasions, and I underwent fecal occult blood testing and a Helicobacter pylori blood test, both of which came back normal.
My total bilirubin level is 33 umol/L, and my eGFR is greater than 90.
I previously had an ultrasound of my liver and kidneys, which indicated some fatty liver.
My doctor said that I am overly anxious, which has led to some tension headaches, but I sometimes worry about my gastrointestinal and liver-kidney conditions.
Should I consider getting an endoscopy and further liver and kidney evaluations? Thank you.

Alvin, 40~49 year old female. Ask Date: 2016/09/26

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, if you are experiencing persistent discomfort in the upper abdomen, you may consider undergoing an upper gastrointestinal endoscopy.
There doesn't seem to be any urgency regarding other issues, so you can continue to monitor your condition.
Changhua Hospital cares about your health.
Chen Shidian.

Reply Date: 2016/09/26

More Info


When it comes to gastrointestinal and liver health, understanding when to seek further testing is crucial, especially if you're experiencing discomfort or unusual symptoms. Based on your description, it seems you have been experiencing persistent gastric discomfort, occasional pain, and have noticed blood in your stool on two occasions. While your recent tests for occult blood and Helicobacter pylori were negative, and your liver function tests indicated a total bilirubin level of 33 umol/L with an eGFR greater than 90, there are several factors to consider in deciding whether further testing, such as an endoscopy (gastroscopy) or additional liver and kidney evaluations, is necessary.

Firstly, the presence of blood in your stool, even if it was not detected in the recent tests, is a symptom that should not be overlooked. It can indicate various conditions ranging from benign issues like hemorrhoids to more serious conditions such as gastrointestinal bleeding, ulcers, or even malignancies. Given that you have a history of gastrointestinal discomfort and have seen blood in your stool, it is advisable to discuss the possibility of a gastroenterology referral for an endoscopy. This procedure allows for direct visualization of the upper gastrointestinal tract and can help identify any abnormalities such as ulcers, inflammation, or lesions that may be causing your symptoms.

Additionally, your elevated total bilirubin level may warrant further investigation. While a bilirubin level of 33 umol/L is not excessively high, it is essential to consider the context of your overall liver health, especially since you have been diagnosed with fatty liver disease. Fatty liver can progress to more severe liver conditions, including non-alcoholic steatohepatitis (NASH) and cirrhosis, if not managed properly. Regular monitoring of liver enzymes such as ALT (GPT) and AST (GOT), along with lipid profiles (triglycerides and cholesterol levels), is recommended to assess liver function and overall health. If these tests show abnormalities, further imaging studies or even a liver biopsy may be warranted to evaluate the extent of liver damage.

Moreover, your mention of feeling anxious and experiencing tension headaches could also be contributing to your gastrointestinal symptoms. Stress and anxiety can exacerbate gastrointestinal issues, leading to conditions like functional dyspepsia or irritable bowel syndrome (IBS). It may be beneficial to explore stress management techniques, such as cognitive behavioral therapy, mindfulness, or relaxation exercises, alongside any medical evaluations.

In summary, given your symptoms and medical history, it would be prudent to pursue further testing. An endoscopy can provide valuable insights into your gastrointestinal health, while regular monitoring of liver function tests will help manage your fatty liver condition. Additionally, addressing any underlying anxiety may improve your overall well-being and potentially alleviate some gastrointestinal discomfort. Always consult with your healthcare provider to discuss your symptoms and the best course of action tailored to your specific situation.

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