Neuromuscular Symptoms: Insights from Brain MRI Findings - Neurology

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Neuromuscular, brain MRI?


Hello, doctor.
In recent months, I have undergone examinations related to neuromuscular issues at a large hospital, including thyroid tests, EEG, and nerve conduction studies, all of which showed no abnormalities.
However, due to the persistence of my symptoms, I have continued taking medication.
During my check-up, I informed the doctor that I experience muscle twitching and neuropathic pain (in my hands, feet, and face), and occasionally my palms become completely numb.
Yesterday, during a follow-up visit, the attending physician asked about my symptoms again.
When testing my nerve responses, the doctor found that the reflex intensity on my left side was greater than that on my right side (right hand and foot).
Additionally, the symptoms I experience are more frequent on the left side of my body compared to the right side.
The doctor arranged for an MRI of my brain, suspecting there might be an issue in the right hemisphere.
I would like to ask if having a stronger reflex on the left side compared to the right side is considered normal.
Thank you.

Xyz, 10~19 year old female. Ask Date: 2016/10/01

Dr. Lan Shengxing reply Neurology


Generally, both sides should be symmetrical, but it is possible for one side to be slightly stronger, which can be normal but may also indicate a central nervous system abnormality.
This physician is quite responsible and has arranged for tests to rule out brain diseases; we will just wait for the results.

Reply Date: 2016/10/01

More Info


Understanding neuromuscular symptoms can be complex, especially when they are accompanied by neurological findings. In your case, the symptoms you describe—muscle twitching, nerve pain, and occasional numbness—are concerning and warrant thorough investigation. Given that you have already undergone several tests, including thyroid function tests, EEG, and nerve conduction studies, and that these have returned normal results, the next logical step is to evaluate the brain through MRI.

The MRI of the brain is a powerful tool for identifying structural abnormalities that could be contributing to your symptoms. It can reveal lesions, tumors, or other pathological changes in brain tissue that might not be visible through other diagnostic methods. In your case, the physician's observation that the reflexes on your left side are stronger than those on the right side is significant. This asymmetry could indicate a neurological issue, potentially involving the right hemisphere of the brain, which controls motor function on the left side of the body.

Asymmetrical reflexes can be a normal variant in some individuals, but when accompanied by symptoms like muscle twitching and pain, they may suggest an underlying condition that needs to be addressed. The MRI will help determine if there are any lesions or abnormalities in the right hemisphere that could explain the increased reflex activity and the symptoms you are experiencing.

It's important to note that while MRI is excellent for visualizing structural issues, it does not assess functional aspects of the brain directly. If the MRI results are normal, further functional imaging studies, such as PET or SPECT scans, may be considered to evaluate brain metabolism and function. These tests can provide insights into how different areas of the brain are working, which can be particularly useful in diagnosing conditions like multiple sclerosis, neurodegenerative diseases, or other disorders that may not present with obvious structural changes.

In summary, the symptoms you are experiencing, particularly the asymmetry in reflexes and the specific neuromuscular complaints, warrant a comprehensive evaluation through MRI. This imaging will help rule out any significant structural abnormalities in the brain that could be contributing to your symptoms. If the MRI is normal, further discussions with your neurologist about additional testing or referrals to specialists in neuromuscular disorders may be necessary to get to the root of your symptoms. Always ensure that you maintain open communication with your healthcare provider about your symptoms and any changes you notice, as this will aid in the diagnostic process and management of your condition.

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