the Effects of Menstrual Regulation Medications for PCOS

I would like to know the effects of menstrual regulation medications?

I have polycystic ovary syndrome (PCOS) without obvious symptoms such as obesity or hirsutism.
Previously, I often experienced missed periods for 2 to 3 months.
After visiting a clinic and undergoing an ultrasound, I was diagnosed.
I have been consistently visiting the same clinic and have been prescribed DOMPERIDONE F.C.
TAB and REMEXIN TABLETS to take at fixed times for 8 days each month.
I have been on these medications for almost six months now (initially, I was prescribed other medications, but they made me feel nauseous, so the doctor switched me to these, although I still experience nausea a few hours after taking them, but it’s not severe).
I start taking them at the beginning of the month, and my period usually arrives around the middle of the month.
I would like to know:
1.
Do these medications induce ovulation and then lead to menstruation, or do they simply thicken the uterine lining to facilitate menstruation?
2.
If it is the latter, what impact does prolonged anovulation have on future fertility?
3.
Is this current method of regulating my menstrual cycle the best option, or are there better alternatives available for me to consider?
Thank you for your assistance.

Yee, 10~19 year old female. Ask Date: 2016/10/02

Dr. Cao Guotao reply Obstetrics and Gynecology

Hello, the medication you are currently taking is exogenous hormones.
It is recommended to consider taking ovulation pills; you can discuss this with your physician.
Wishing you good health.

Reply Date: 2016/10/02

More Info

Understanding the effects of menstrual regulation medications for Polycystic Ovary Syndrome (PCOS) is crucial for managing symptoms and improving reproductive health. In your case, you are taking DOMPEDON F.C. and REMEXIN TABLETS to regulate your menstrual cycle. Let's break down your questions regarding these medications and their implications for your health.

1. Mechanism of Action: DOMPEDON (Domperidone) is primarily an antiemetic medication that helps control nausea and vomiting. It works by blocking dopamine receptors in the gut, which can also influence the gastrointestinal tract's motility. While it is not directly involved in ovulation or menstrual regulation, it may help alleviate nausea associated with other medications. On the other hand, REMEXIN (likely a form of a hormonal medication, possibly a combination of estrogen and progestin) is used to help regulate the menstrual cycle. This medication can help thicken the uterine lining, which is essential for a regular menstrual cycle. If ovulation occurs, it can lead to menstruation; if not, it may still induce a withdrawal bleed by shedding the thickened lining. Therefore, while REMEXIN can help regulate your cycle, it does not necessarily induce ovulation.

2. Long-term Effects of Anovulation: If you are experiencing long periods without ovulation (anovulation), it can have implications for your fertility. Anovulation can lead to irregular menstrual cycles and may increase the risk of endometrial hyperplasia (thickening of the uterine lining), which can potentially lead to endometrial cancer if left untreated. Additionally, long-term anovulation can affect your hormonal balance, leading to symptoms such as irregular periods, weight gain, and increased risk of metabolic syndrome. Therefore, it is essential to address the underlying hormonal imbalances associated with PCOS to improve your chances of ovulation and overall reproductive health.

3. Best Practices for Menstrual Regulation: The current approach of using DOMPEDON and REMEXIN may be effective for managing your symptoms, but it is essential to evaluate whether this is the best long-term strategy. Other options for managing PCOS and regulating menstrual cycles include lifestyle modifications (such as diet and exercise), insulin-sensitizing agents like Metformin, and hormonal contraceptives that can help regulate periods and reduce symptoms associated with PCOS. It is crucial to have an open discussion with your healthcare provider about your treatment plan, including any side effects you may be experiencing, such as nausea. If the current medications are causing discomfort, your doctor may consider alternative treatments that could be more effective and better tolerated.

In summary, while the medications you are taking can help regulate your menstrual cycle, it is essential to understand their mechanisms and implications for your reproductive health. Addressing the underlying issues of PCOS through a comprehensive approach that includes lifestyle changes and possibly other medications can help improve your symptoms and fertility outcomes. Always consult with your healthcare provider to tailor a treatment plan that best suits your needs and addresses any concerns you may have.

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