CT Scan Results: Evaluating Lung Tumors and Biopsy Risks - Pulmonology

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A chest CT scan revealed several tumors approximately four centimeters in size?


Hello Doctor: My father was suddenly hospitalized on October 8, 2016, due to a high fever and respiratory distress with wheezing.
After a chest CT scan, a dark spot was found on the right side of his chest, and the doctor recommended a chest computed tomography (CT) scan.
Since the doctor was not on rounds during the holiday, the scan was scheduled for today, October 11, 2016, in the afternoon.
The report indicated several tumors approximately four centimeters in size compressing the bronchus, and the doctor suggested performing a bronchoscopy with biopsy for testing the following afternoon.
Due to my father's high fever and persistent diarrhea over the past few days, he is in a weakened state.
I would like to ask Dr.
Huang two questions: First, is it advisable for my father to undergo bronchoscopy with biopsy while in a weakened condition? (He has been on anticoagulants for over a year.) Second, can we confirm that it is a tumor? Given my father's nearly twenty-year history of diabetes and two previous episodes of pulmonary tuberculosis, could it be pulmonary tuberculosis nodules? Thank you!

Jessica Huang, 40~49 year old female. Ask Date: 2016/10/11

Dr. Huang Yiwen reply Pulmonology


DEAR JESSICA: Currently, you are on anticoagulants, and you need to stop them for at least a week before the examination.
A tuberculoma is a possibility, but four centimeters is somewhat large.
It would be best to find old films for comparison, as this may eliminate the need for some tests.
Changhua Hospital cares about you.

Reply Date: 2016/10/11

More Info


When interpreting CT scan results, especially concerning lung tumors, it is essential to consider both the imaging findings and the clinical context. In your father's case, the CT scan revealed several tumors approximately four centimeters in size, which are compressing the bronchus. This finding is concerning for malignancy, but it is crucial to confirm the diagnosis through further testing, such as a biopsy.


Addressing Your Questions:
1. Is it safe for your father to undergo a bronchoscopy for biopsy given his weakened state?
- Bronchoscopy is a minimally invasive procedure, but it does carry risks, especially in patients who are already in a compromised state. Given that your father has been experiencing high fever and diarrhea, his overall health may not be optimal for such a procedure. Additionally, the use of anticoagulants can increase the risk of bleeding during and after the biopsy. It is essential for the medical team to evaluate his current health status, including his vital signs, laboratory results, and overall physical condition, before proceeding. If the risks outweigh the benefits, the medical team may consider alternative diagnostic methods or postpone the procedure until he is in a more stable condition.

2. Could the findings be indicative of tuberculosis rather than a tumor?
- Your father's medical history of diabetes and previous tuberculosis infections raises the possibility of pulmonary complications related to these conditions. Tuberculosis can present as nodules or masses in the lungs, and it can sometimes mimic malignancy on imaging studies. However, the size of the lesions and their compressive effects on the bronchus are more suggestive of a neoplastic process. To differentiate between a malignant tumor and a tuberculous lesion, a biopsy is necessary. The biopsy will provide histological confirmation, which is crucial for determining the appropriate treatment plan.


Additional Considerations:
- Imaging Follow-Up: If the bronchoscopy is delayed or deemed too risky, other imaging modalities, such as PET scans, may be utilized to assess metabolic activity in the lesions, which can provide additional insights into their nature.

- Multidisciplinary Approach: It is essential to involve a multidisciplinary team, including pulmonologists, oncologists, and infectious disease specialists, to evaluate the best course of action for your father. They can help weigh the risks and benefits of proceeding with a biopsy versus monitoring the situation.

- Patient Support: Given the emotional toll that such findings can have on patients and their families, it is also vital to ensure that your father receives psychological support during this challenging time.

In conclusion, while the CT findings are concerning for malignancy, further evaluation through biopsy is necessary to confirm the diagnosis. The decision to proceed with the biopsy should be made carefully, considering your father's current health status and the potential risks involved. It is advisable to have an open discussion with his healthcare team to explore all available options and make an informed decision.

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