Can Taking Folic Acid with Vitamin C Affect My Pregnancy? - Obstetrics and Gynecology

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I would like to inquire about the combination of folic acid and vitamin C?


Hello Doctor, I previously took folic acid along with vitamin C during my pregnancies.
After becoming pregnant, I continued to take folic acid and vitamin C until I reached 6 weeks.
However, I later found out online that folic acid and vitamin C should not be taken together, as it may hinder absorption.
Now that I am 7 weeks pregnant and aware that folic acid and vitamin C should not be consumed together, I am only taking folic acid.
I would like to ask if there will be any effects from having taken them together previously? Will it affect the fetus? Also, now that I am about 7 weeks pregnant, is there any additional nutrition I can supplement to mitigate the effects of having taken folic acid and vitamin C together? Thank you.

Angie, 20~29 year old female. Ask Date: 2016/11/23

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, consuming folic acid through a balanced diet should be sufficient, and there may be no need for any nutritional supplements.
Wishing you good health!

Reply Date: 2016/11/23

More Info


Taking folic acid and vitamin C together during pregnancy is a concern for some, but the evidence regarding their interaction is not definitive. Folic acid is crucial for fetal development, particularly in preventing neural tube defects, while vitamin C plays a role in immune function and collagen synthesis.
The primary concern about taking these two vitamins together stems from the belief that vitamin C may degrade folic acid in the gastrointestinal tract, potentially reducing its absorption. However, research has not conclusively shown that this interaction significantly impacts the overall effectiveness of folic acid supplementation when taken in reasonable amounts.
In your case, since you have been taking both folic acid and vitamin C during the early weeks of your pregnancy, it is understandable to be concerned about any potential effects on your developing fetus. However, it is important to note that the critical period for neural tube development occurs within the first 28 days of conception. If you have been taking folic acid consistently, you have likely provided your baby with the necessary levels of this vital nutrient during this crucial time.

At 7 weeks pregnant, it is advisable to continue taking folic acid as recommended by your healthcare provider. If you are concerned about your previous intake of both vitamins, it may be helpful to consult with your obstetrician or a registered dietitian. They can provide personalized advice based on your specific situation and dietary needs.

In terms of additional nutrients, focusing on a balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats is essential. Foods high in folate, such as leafy greens, legumes, and fortified cereals, can further support your folic acid intake. Additionally, consider incorporating foods rich in vitamin C, like citrus fruits, strawberries, and bell peppers, to support your overall health and immune function.

If you are still worried about the potential effects of taking both vitamins together, rest assured that the body is quite resilient, and many women have taken both without adverse effects. The key is to maintain a balanced approach to nutrition and follow your healthcare provider's recommendations.

In summary, while there is some concern regarding the simultaneous intake of folic acid and vitamin C, the evidence does not strongly support significant negative effects on pregnancy outcomes. Continue taking folic acid, maintain a healthy diet, and consult with your healthcare provider for any further questions or concerns. Your proactive approach to your health and your baby's well-being is commendable, and staying informed is an essential part of a healthy pregnancy.

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