Do Nursing Students Need a Complete Hepatitis B Vaccine Series? - Gastroenterology and Hepatology

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Hepatitis B vaccination?


Hello, doctor.
I am a nursing student and I will be going for my internship in mid-February.
In 2013, I received a booster vaccine at school, but my recent blood test shows that I no longer have antibodies.
Do I need to receive three doses of the vaccine? Will I be able to produce antibodies after the first dose (I will definitely complete all three doses)? I'm concerned about the timing for my internship and whether I should just get an additional dose now.
However, I'm also worried that the antibodies might diminish quickly again.

Yingying, 10~19 year old female. Ask Date: 2017/01/03

Dr. Cai Anshun reply Gastroenterology and Hepatology


Hello: Some individuals exhibit a strong antibody response after receiving the first dose, while others may not produce antibodies at all, and some may only show a very weak antibody response.
This can vary from person to person.
However, if all three doses are completed, those who initially had a weak antibody response may see an enhancement.
Of course, there are also cases where individuals do not develop antibodies even after receiving all three doses.
Changhua Hospital cares about your health.
Dr.
Tsai An-shun.

Reply Date: 2017/01/03

More Info


As a nursing student preparing for clinical practice, it's crucial to ensure that you are adequately protected against Hepatitis B, especially since you will be in an environment where you may be exposed to blood and bodily fluids. Given your situation, let's break down the considerations regarding the Hepatitis B vaccination series and the need for additional doses.

Firstly, the Hepatitis B vaccine is typically administered in a series of three doses, following the schedule of 0, 1, and 6 months. This schedule is designed to provide optimal immunity against the virus. If your blood test indicates that you no longer have detectable antibodies, it suggests that your immunity has waned, which can happen over time, especially if you were vaccinated many years ago.

In your case, since you mentioned that you received a booster dose in the past (102 years ago, which I assume is a typo and should be 2012), and now your antibody levels are undetectable, it is advisable to complete the vaccination series again. The Centers for Disease Control and Prevention (CDC) recommends that individuals who are at risk for Hepatitis B, such as healthcare workers and nursing students, ensure they are fully vaccinated and have adequate antibody levels.

Regarding your concern about whether you will develop antibodies after the first dose of the vaccine, it is important to note that while some individuals may develop protective antibodies after the first dose, many will not. The immune response can vary significantly from person to person. Therefore, completing the full three-dose series is the best approach to ensure that you achieve adequate immunity.

If you are worried about timing, consider that the first dose can be administered as soon as possible, and you can continue with the subsequent doses according to the recommended schedule. The first dose will provide some level of protection, but it is the completion of the series that will ensure long-term immunity.
In terms of your practical concerns about timing for your upcoming clinical practice, it is generally safe to start the vaccination series even if you are close to your start date. The first dose can be given, and you can schedule the second and third doses accordingly. It is also worth noting that the immune response can take some time to develop, so starting the series as soon as possible is critical.

In summary, as a nursing student, you should complete the Hepatitis B vaccination series to ensure you are protected during your clinical practice. It is recommended to receive all three doses, as this will provide the best chance of developing long-lasting immunity. If you have any further questions or concerns, please consult with your healthcare provider or the occupational health department at your school, as they can provide guidance tailored to your specific situation.

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