Do I Need to Revaccinate for Hepatitis B After Incomplete Shots? - Gastroenterology and Hepatology

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Hepatitis B vaccine injection?


If you received the first two doses of the hepatitis B vaccine during your second or third year of high school but did not complete the series with the third or fourth doses, and your recent health check results show HBsAg negative, HBsAb positive, and HBeAg negative, this indicates that you have developed immunity against hepatitis B.

The presence of HBsAb (hepatitis B surface antibody) suggests that your body has successfully responded to the vaccine and you are protected against hepatitis B infection.
Given your family history, it is advisable to consult with a healthcare provider regarding whether you should receive additional doses of the vaccine to ensure long-term immunity.
However, based on your current serological results, you appear to have adequate protection at this time.

kate, 20~29 year old female. Ask Date: 2005/11/02

Dr. Lin Minghui reply Gastroenterology and Hepatology


Hello, a positive HBsAb indicates immunity against hepatitis B.
Generally, the antibody levels from the vaccine may decrease over time, but a decline in levels does not necessarily mean a loss of the ability to fight hepatitis B.
The third dose of the vaccine is primarily to maintain antibody concentration.
If you are in a high-risk group, it is recommended to receive a booster shot.
Sincerely, Dr.
Lin Ming-Hui, Internal Medicine.

Reply Date: 2005/11/02

More Info


Based on the information provided, it appears that you have received the first two doses of the Hepatitis B vaccine during high school, and your recent health check-up results show that you are HBsAg negative, HBsAb positive, and HBeAg negative. This indicates that you have developed immunity against Hepatitis B, which is a positive outcome.

To break it down further:
1. Understanding the Results:
- HBsAg (Hepatitis B surface antigen): A negative result indicates that you are not currently infected with the Hepatitis B virus.

- HBsAb (Hepatitis B surface antibody): A positive result means that you have antibodies against the Hepatitis B virus, which suggests that you have either been vaccinated or have recovered from a past infection. In your case, it indicates that the vaccination you received was effective.

- HBeAg (Hepatitis B e antigen): A negative result typically indicates that there is no active viral replication, which is a good sign.

2. Do You Need to Revaccinate?:
Given that you have a positive HBsAb result, you do not need to revaccinate for Hepatitis B. The presence of antibodies means that your immune system has successfully responded to the vaccine, providing you with protection against the virus. The standard recommendation is that if you have a positive HBsAb, you are considered immune and do not require additional doses of the vaccine.

3. Duration of Immunity:
Immunity from the Hepatitis B vaccine can last for many years, often for at least 10 years or more. However, it is important to note that while the antibodies may decrease over time, this does not necessarily mean that you are no longer protected. Your immune system retains a memory of the virus, which can provide protection even if antibody levels fall.

4. Family History Considerations:
Given your family history of Hepatitis B, it is wise to remain vigilant about your health. Regular check-ups and monitoring of your liver health are advisable, especially since your father is a carrier and your grandfather had liver cancer. While your current results are reassuring, maintaining a proactive approach to your health is essential.

5. Future Recommendations:
- Continue to monitor your health with regular check-ups.

- If you have any concerns about your immunity or potential exposure to Hepatitis B, consult with your healthcare provider for personalized advice.

- If you ever have a situation where you might be at risk of exposure (e.g., through blood or bodily fluids), discuss with your doctor whether any additional precautions or vaccinations are necessary.

In conclusion, based on your current health check results, you do not need to receive additional doses of the Hepatitis B vaccine. You have demonstrated immunity, and it is important to continue monitoring your health, especially considering your family history. Always consult with your healthcare provider for any specific concerns or changes in your health status.

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