Do Antipsychotics Contain Steroids? Side Effects and Risks - Psychiatry

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Antipsychotic medications, such as Zyprexa (olanzapine) and Seroquel (quetiapine), do not contain steroids. However, they can lead to significant side effects, including weight gain, metabolic changes, and alterations in body composition. The symptoms you describe, such as increased appetite, weight gain, a rounded face (often referred to as "moon face"), and fat accumulation in the neck and abdomen, are commonly associated with certain antipsychotic medications, particularly olanzapine. These medications can disrupt metabolic processes, leading to changes in how the body stores fat and regulates appetite.

The weight gain you experienced, from 45 kg to 58 kg, is concerning, especially given your height of 152 cm. This increase in weight can elevate the risk of developing other health issues, such as type 2 diabetes, hypertension, and dyslipidemia (abnormal lipid levels). The redistribution of fat, particularly to the abdomen, can also increase the risk of cardiovascular diseases.
Regarding your gastrointestinal issues, such as gastroesophageal reflux disease (GERD) and potential ulcers, these can be exacerbated by certain medications, including some antipsychotics and steroids. While steroids are known to increase the risk of gastrointestinal complications, the antipsychotic medications can also contribute to these issues through various mechanisms, including changes in appetite and eating habits.

The side effects you mentioned, such as headaches, dizziness, nausea, and palpitations, can be attributed to several factors, including the medications you are taking. It's essential to discuss these symptoms with your healthcare provider, as they may indicate that your current treatment regimen needs adjustment.
In terms of the relationship between weight gain and the risk of other diseases, it is well-documented that significant weight gain can lead to a host of metabolic and cardiovascular issues. Therefore, it is crucial to monitor your weight and metabolic health regularly. If you are experiencing adverse effects from your medications, your doctor may consider adjusting your dosage or switching to a different medication that has a lower risk of weight gain and metabolic side effects.

In summary, while antipsychotics do not contain steroids, they can lead to significant side effects, including weight gain and metabolic changes. It is essential to maintain open communication with your healthcare provider about any side effects you experience and to monitor your health closely to mitigate the risk of developing additional health issues. Regular follow-ups and possibly consulting with a nutritionist or a specialist in metabolic health may also be beneficial in managing these side effects effectively.