Can You Have Intercourse After Taking RU486 Without Contraction Pills? - Obstetrics and Gynecology

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It is not advisable to have unprotected intercourse after taking RU486 (mifepristone) without taking the follow-up medication for uterine contractions. It is important to follow the prescribed medical guidelines and consult with a healthcare professional for personalized advice?


Hello doctor, my girlfriend and I took RU486 at the gynecology clinic yesterday and took the medication on-site.
The next afternoon, we had intercourse and I ejaculated inside her.
Will this have any effect on the medication or any other implications?

Niming, 20~29 year old female. Ask Date: 2017/02/19

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, generally it does not have an impact.
Wishing you good health.

Reply Date: 2017/02/19

More Info


RU486, also known as mifepristone, is a medication commonly used for medical abortion. It works by blocking the hormone progesterone, which is necessary for the continuation of pregnancy. After taking RU486, it is crucial to understand the implications of engaging in sexual intercourse, especially if the intention is to terminate a pregnancy.

Firstly, after taking RU486, it is generally recommended to wait until the abortion process is complete before engaging in sexual intercourse. This is because the medication can cause significant changes in the body, including bleeding and cramping, which are part of the abortion process. Engaging in intercourse during this time can increase the risk of infection, as the cervix may be slightly open, allowing bacteria to enter the uterus. Additionally, if the abortion is not complete, there is a risk of pregnancy continuing, which could lead to complications.

If your girlfriend has taken RU486, it is typically followed by a second medication, misoprostol, which is taken 24 to 48 hours later. Misoprostol induces contractions to help expel the pregnancy tissue from the uterus. If she has not taken this second medication yet, or if the abortion process has not been confirmed as complete, having intercourse could pose risks.

Regarding the timing of sexual activity, it is advisable to wait until a follow-up appointment with a healthcare provider confirms that the abortion is complete. This usually occurs about one to two weeks after taking the medications. During this follow-up, a healthcare provider may perform an ultrasound or a physical examination to ensure that the uterus is clear of any remaining tissue.

In terms of the specific question about the effects of having intercourse after taking RU486 without contraction pills, it is essential to consider the following points:
1. Risk of Infection: As mentioned, engaging in intercourse before the abortion is complete can increase the risk of infection. It is crucial to maintain good hygiene and be aware of any unusual symptoms, such as fever, severe pain, or foul-smelling discharge, which could indicate an infection.

2. Effectiveness of the Medication: Having intercourse does not affect the effectiveness of RU486 itself, but if the abortion is not complete, there is a possibility of continuing the pregnancy. If there are any concerns about this, it is essential to consult a healthcare provider.

3. Emotional and Physical Well-being: The process of a medical abortion can be emotionally and physically taxing. It is important for both partners to communicate openly about their feelings and ensure that they are both comfortable with any sexual activity during this time.

4. Contraceptive Considerations: If there is any chance of pregnancy continuing, it is advisable to discuss contraceptive options with a healthcare provider. After a medical abortion, fertility can return quickly, so discussing birth control methods is essential if the couple wishes to avoid unintended pregnancy in the future.

In conclusion, while it is technically possible to have intercourse after taking RU486, it is not advisable until the abortion process is confirmed as complete. It is crucial to prioritize health and safety by consulting with a healthcare provider for personalized advice and follow-up care.

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