Can I Have Sex After Taking the First Dose of RU486? - Obstetrics and Gynecology

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Can I have intercourse after taking the first dose of RU486?


Hello, I took the first dose of RU486 on March 19 at 3:00 PM, and I had intercourse on March 20 at 11:00 AM.
Will this affect the efficacy of the medication? Thank you!

M, 30~39 year old female. Ask Date: 2022/03/20

Dr. Cao Guotao reply Obstetrics and Gynecology


Hello, it generally does not have an impact.
Wishing you good health.

Reply Date: 2022/03/20

More Info


After taking the first dose of RU486 (mifepristone), it is generally considered safe to have sexual intercourse. RU486 is primarily used for medical abortion and works by blocking the hormone progesterone, which is necessary for maintaining a pregnancy. The first dose of RU486 does not immediately terminate a pregnancy; it prepares the body for the subsequent dose of prostaglandin (usually taken 24 to 48 hours later), which induces uterine contractions to expel the pregnancy tissue.

In your case, having sexual intercourse the day after taking the first dose of RU486 should not affect the efficacy of the medication. The primary concern with having sex during this time is not about the effectiveness of RU486, but rather about the potential for unintended pregnancy if the abortion process has not yet been completed. Since the first dose does not immediately result in the termination of pregnancy, there is still a risk of pregnancy if you engage in unprotected sex.

It is important to note that after taking RU486, the body may still be in a state where it could potentially conceive again if no additional contraceptive measures are taken. Therefore, if you are not planning to become pregnant again, it is advisable to use contraception, such as condoms or hormonal birth control, after the abortion process is complete.

Additionally, after the abortion is confirmed to be complete (usually by a follow-up appointment with a healthcare provider), you can resume your regular contraceptive methods. If you were already using birth control before taking RU486, you can typically continue using it as directed once your next menstrual cycle begins.

In summary, while having sex after taking the first dose of RU486 does not affect the medication's efficacy, it is crucial to consider the risk of unintended pregnancy. If you have further concerns or questions about your specific situation, it is always best to consult with your healthcare provider for personalized advice and guidance. They can provide you with information on when it is safe to resume sexual activity and what contraceptive methods may be appropriate for you moving forward.

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Hello, I took the first dose of RU486 on March 19 at 3:00 PM, and had intercourse on March 20 at 11:00 AM. Will this affect the efficacy of the medication? Thank you!


Dr. Cao Guotao reply Obstetrics and Gynecology
Hello, it generally does not have an impact. Wishing you good health.

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