Concerns About Doxycycline Dosage for Chlamydia Treatment - Internal Medicine

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Last week, I was diagnosed with Chlamydia, and my doctor prescribed me doxycycline for two weeks, instructing me to take one pill in the morning and one in the evening.
However, I forgot the dosage schedule and have only been taking one pill each night for the past week.
Now I have 19 pills left.
Should I start taking one pill in the morning and one in the evening starting tomorrow? Will only taking one pill each day this week render the treatment ineffective? I am really worried and hope to get an answer.
Thank you.

Li, 20~29 year old female. Ask Date: 2017/03/04

Dr. Liao Zhongxin reply Internal Medicine


Dear readers: A: Since it has been confirmed and a decision has been made to treat it, it is advisable to finish the remaining 19 pills as scheduled; then, follow up with the original diagnosing physician.
Thank you!

Reply Date: 2017/03/04

More Info


Doxycycline is a tetracycline antibiotic commonly prescribed for various bacterial infections, including Chlamydia. It is effective in treating this sexually transmitted infection due to its ability to inhibit bacterial protein synthesis, thereby stopping the growth of the bacteria. The standard dosage for treating Chlamydia is typically 100 mg taken twice daily for seven days. However, in your case, your doctor has prescribed a two-week course, which is not uncommon for certain infections or patient circumstances.

Given that you have been taking only one dose per day instead of the prescribed two, it is understandable to be concerned about the effectiveness of the treatment. Taking doxycycline as directed is crucial for ensuring that the medication can effectively eliminate the infection. Missing doses can lead to suboptimal drug levels in your system, which may not be sufficient to fully eradicate the bacteria. This could potentially result in treatment failure or the development of antibiotic resistance.

Here are some important points to consider regarding your situation:
1. Restarting the Dosage: It is advisable to resume the prescribed dosage of doxycycline as soon as possible. This means taking one capsule in the morning and one in the evening. However, do not double up on doses to make up for the missed ones. Instead, just continue with the regular schedule from this point forward.

2. Consult Your Doctor: Given your concerns about the effectiveness of the treatment due to missed doses, it is essential to communicate with your healthcare provider. They may want to evaluate your situation further and could recommend additional testing or a different treatment plan if necessary.

3. Potential Side Effects: While doxycycline is generally well-tolerated, it can cause side effects such as nausea, vomiting, diarrhea, and photosensitivity (increased sensitivity to sunlight). If you experience severe side effects or symptoms that concern you, seek medical advice promptly.

4. Importance of Adherence: Adhering to the prescribed medication regimen is crucial not only for your health but also for public health. Incomplete treatment can lead to the spread of Chlamydia to others and may contribute to the development of antibiotic-resistant strains of bacteria.

5. Follow-Up Care: After completing your course of doxycycline, it is important to follow up with your healthcare provider to ensure that the infection has been cleared. They may recommend a test of cure, especially if you had symptoms or if you are at high risk for reinfection.

In summary, you should resume taking doxycycline as prescribed (one capsule in the morning and one in the evening) without trying to compensate for the missed doses. Reach out to your healthcare provider to discuss your concerns and ensure that you receive the appropriate care. Remember, effective communication with your healthcare team is key to managing your health and ensuring successful treatment outcomes.

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