Medication Use During Pregnancy Preparation: Safety and Timing Concerns - Pharmacology

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Medications for Pregnancy Preparation


Hello, I am currently preparing for pregnancy but took the following medications for a cold (for 3 days), and the next day my menstrual period arrived (but the flow was lighter).
Will this affect my fertility? How long should I wait before trying to conceive? Thank you.

The medications taken include:
- Voren 1 tablet
- Wetunlin 1 tablet
- Clarithromycin 0.5 tablet
- Benproperine 20mg 1 tablet
- Kezintea 4mg 0.5 tablet
- Lysozyme 1 tablet
- Anltone (Acelamino) 1 tablet
- Deallergy (Zylec) 1 tablet
- Benproperine 20mg 1 tablet

CHI, 30~39 year old female. Ask Date: 2017/03/19

Dr. Liao Huiling reply Pharmacology


During the preconception phase, short-term use of cold medications will not have adverse effects.

Reply Date: 2017/03/19

More Info


When considering medication use during pregnancy preparation, it is essential to understand the potential implications of any medications taken prior to conception. The medications you mentioned—Voren, Wetunlin, Clarithromycin, Benproperine, Kezintea, Lysozyme, Anltone (Acelamino), and Deallergy (Zylec)—each have different safety profiles and classifications regarding their use during pregnancy.

1. Clarithromycin: This antibiotic is classified as Category C, which means that risk cannot be ruled out. Animal studies have shown adverse effects, but there are no adequate and well-controlled studies in pregnant women. Therefore, it should only be used if the potential benefit justifies the potential risk to the fetus.

2. Benproperine: This medication is generally used as a cough suppressant. Its safety during pregnancy has not been well established, and it is advisable to use it cautiously.

3. Kezintea: This medication is an antihistamine, and while many antihistamines are considered relatively safe during pregnancy, specific safety data for Kezintea may not be well documented.

4. Lysozyme: This is an enzyme that has antibacterial properties. It is generally considered safe, but specific data on its use during pregnancy is limited.

5. Anltone (Acelamino): This medication is often used for pain relief and fever reduction. Its safety during pregnancy is not well established, and it is advisable to consult a healthcare provider.

6. Deallergy (Zylec): This is an antihistamine, and like other antihistamines, it may be used during pregnancy, but caution is advised.

7. Voren and Wetunlin: These medications are less commonly referenced in pregnancy safety literature, and their specific effects during pregnancy are not well documented.

Given that you have taken these medications for three days and your menstrual cycle has started, it is unlikely that they would have a significant impact on your ability to conceive. However, the timing of conception after medication use can vary based on the specific medications and their half-lives. Generally, it is advisable to wait at least one menstrual cycle after taking any medications that are not well-studied for safety in pregnancy, allowing your body to clear the medications and return to its natural state.

In conclusion, while the medications you have taken may not pose a significant risk, it is crucial to consult with your healthcare provider regarding their specific safety profiles and the timing of conception. They can provide personalized advice based on your health history and the medications involved. Additionally, if you are planning to conceive, it is always best to discuss any medications you may need to take during this period with your healthcare provider to ensure both your health and the health of your future pregnancy.

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