Is Surgery Necessary After Radiation for Stage 3B Cervical Cancer? - Oncology

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Radiation Therapy


Hello, the patient is a 73-year-old woman diagnosed with stage 3B cervical cancer.
She has undergone 28 sessions of external beam radiation therapy and 3 sessions of chemotherapy during the radiation treatment.
Due to hospital equipment limitations, she did not receive brachytherapy.
It has been over three months since treatment, and currently, there are no signs of recurrence.
Given her age and the current stage of her cancer, is surgery a necessary option if brachytherapy is not pursued, or is monitoring sufficient? Thank you.

Niming, 40~49 year old female. Ask Date: 2017/04/19

Dr. Chen Sirong reply Oncology


Anonymous / 49 years old / Male
Is surgery a necessary option at this stage and age if further brachytherapy is not performed, or is monitoring sufficient?
A: 1.
If no adjuvant brachytherapy is performed, it means that the radiation dose is insufficient, as the effective dose should be 8000 cGy, which increases the risk of recurrence.
2.
Now that three months have passed, adding additional radiation therapy will have limited effectiveness because the previous treatment was not delivered continuously.
The additional 3000 cGy will not effectively combine with the previous 5040 cGy dose, so it still won't reach the therapeutic effect of 8000 cGy.
3.
Therefore, it is best to proceed with surgery if possible.
4.
If the gynecologist determines that surgery is not feasible, then monitoring is the only option.
Wishing you good health,
Taoyuan Hospital,
Chen Sih-Rong

Reply Date: 2017/04/19

More Info


When considering the management of Stage 3B cervical cancer, particularly after radiation therapy, the decision regarding the necessity of surgery is complex and should be tailored to the individual patient's circumstances. In your mother's case, she has undergone external beam radiation therapy (EBRT) and concurrent chemotherapy, which is a standard treatment approach for locally advanced cervical cancer. The absence of recurrence signs after three months is a positive indicator, but it does not eliminate the need for careful consideration of further treatment options.


Understanding Stage 3B Cervical Cancer
Stage 3B cervical cancer indicates that the cancer has spread to the pelvic wall and/or the lower third of the vagina, but it has not metastasized to distant sites. The treatment typically involves a combination of radiation and chemotherapy, as you mentioned. The goal of this treatment is to control the disease and improve survival rates.

Role of Surgery
In many cases of locally advanced cervical cancer, surgery is not the primary treatment modality due to the extent of the disease. However, surgery can be considered in certain scenarios, particularly if there is a residual tumor after radiation therapy or if the tumor is resectable. The decision to proceed with surgery depends on several factors:
1. Tumor Response: If imaging studies and clinical evaluations indicate a complete response to radiation, surgery may not be necessary. Conversely, if there is evidence of residual disease, surgical intervention might be warranted.

2. Patient’s Overall Health: At 73 years old, your mother's overall health, functional status, and ability to tolerate surgery are critical considerations. If she has significant comorbidities or frailty, the risks associated with surgery may outweigh the potential benefits.

3. Potential Benefits vs. Risks: The potential benefits of surgery include the possibility of removing any residual cancer and improving long-term survival. However, the risks include surgical complications, longer recovery times, and the impact on her quality of life.

4. Follow-Up and Monitoring: Given that your mother has shown no signs of recurrence, a careful follow-up plan with regular imaging and clinical assessments may be appropriate. This approach allows for monitoring of any changes in her condition without the immediate need for surgery.


Conclusion
In conclusion, whether surgery is necessary after radiation for Stage 3B cervical cancer is not a straightforward answer and should be made in consultation with her oncologist. If the oncologist believes that the benefits of surgery outweigh the risks, it may be recommended. However, if the current status shows no recurrence and her health allows for close monitoring, a watchful waiting approach with regular follow-ups may be more suitable.

It is essential to have an open discussion with her healthcare team about the potential risks and benefits of surgery versus continued monitoring. They can provide personalized recommendations based on her specific clinical situation, overall health, and preferences.

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