Testosterone Testing and Erectile Dysfunction Issues - Urology

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Blood test for testosterone and erectile dysfunction issues?


Hello Doctor, I would like to ask two questions.
The first is about blood tests for testosterone.
During the Mid-Autumn Festival last year, I went to a large hospital and fasted for either 8 or 12 hours before having my testosterone levels checked.
The results showed higher than normal levels, so I concluded it might be psychological.
However, I have recently been experiencing difficulty with erections, so I consulted with a family medicine doctor regarding psychological and adrenal issues.
The family medicine doctor did not have access to my lab results from last year and wanted to conduct another testosterone test.
I paid out of pocket for the blood test, but it just occurred to me that on that day, it was my first visit to that clinic and I did not fast before the blood draw.
Would the testosterone test results be accurate under those circumstances?
The second question is about engorgement.
During my visit, the family medicine doctor mentioned that even with sufficient testosterone, poor penile engorgement could also lead to difficulties with erections.
So, setting aside psychological factors, could inadequate penile engorgement be a contributing factor to erectile difficulties even when testosterone levels are adequate? If so, should I go to a urologist and explain that my testosterone levels are sufficient, and ask the doctor to evaluate my penile engorgement capacity? I appreciate your response to these two questions.
Thank you.

Mr. Nan, 30~39 year old female. Ask Date: 2017/04/20

Dr. Du Shixi reply Urology


Hello: There are many factors affecting sexual function.
Even with sufficient testosterone levels, poor penile engorgement can also be a contributing factor to erectile difficulties.
Yes, but there are other possible factors as well.
Regarding the ability of penile engorgement, it is rare to hear of anyone undergoing such an examination; you may want to consult a medical center for evaluation.
(Fasting for blood tests generally does not significantly affect testosterone levels; I believe the physician may have other fasting-related tests in mind.)

Reply Date: 2017/04/20

More Info


When it comes to testosterone testing and erectile dysfunction (ED), it's important to understand the nuances of hormone levels and their physiological effects. Let's address your two questions in detail.


Question 1: Accuracy of Testosterone Testing Without Fasting
Testosterone levels can fluctuate throughout the day and can be influenced by various factors, including food intake. Typically, testosterone levels are highest in the morning and can decline throughout the day. For accurate measurement, it is generally recommended to have blood drawn in the morning after fasting for at least 8 hours. If you had your blood drawn without fasting, it could potentially affect the accuracy of the testosterone levels reported.
However, the impact of not fasting may not be significant for testosterone testing, as testosterone is not as sensitive to food intake as some other hormones. That said, if your previous test showed elevated levels, and you are experiencing symptoms like erectile dysfunction, it would be wise to discuss this with your healthcare provider. They may recommend retesting under controlled conditions (i.e., fasting and morning draw) to confirm your testosterone levels.


Question 2: Erectile Dysfunction Despite Adequate Testosterone Levels
Erectile dysfunction can be multifactorial, and testosterone is just one piece of the puzzle. Even with adequate testosterone levels, issues with penile blood flow can lead to difficulties in achieving or maintaining an erection. The process of erection involves a complex interplay of psychological, neurological, hormonal, and vascular factors.
If your testosterone levels are confirmed to be within the normal range, but you are still experiencing erectile difficulties, it is indeed possible that the issue lies in the vascular system—specifically, the ability of blood vessels to dilate and allow sufficient blood flow into the penis. This is often referred to as "penile vascular function."
Conditions such as diabetes, hypertension, high cholesterol, and even lifestyle factors like smoking and obesity can impair blood flow and contribute to erectile dysfunction. Therefore, it would be prudent to discuss these concerns with a urologist, who can perform specific tests to evaluate penile blood flow, such as a Doppler ultrasound or other vascular assessments.


Additional Considerations
1. Psychological Factors: Anxiety, stress, and depression can significantly impact sexual function. If psychological factors are suspected, it may be beneficial to consult with a mental health professional who specializes in sexual health.

2. Lifestyle Modifications: Improving lifestyle factors such as diet, exercise, and sleep can have a positive impact on erectile function. Regular physical activity can enhance blood circulation and improve overall health.

3. Further Testing: If the urologist finds that blood flow is inadequate, they may suggest treatments ranging from oral medications (like PDE5 inhibitors) to more advanced options such as vacuum erection devices or penile injections.

4. Hormonal Evaluation: In addition to testosterone, other hormones such as luteinizing hormone (LH), follicle-stimulating hormone (FSH), and prolactin may also be evaluated to rule out other hormonal imbalances that could contribute to erectile dysfunction.

In conclusion, while testosterone levels are important, they are not the sole determinant of erectile function. A comprehensive evaluation that includes both hormonal and vascular assessments, along with consideration of psychological factors, will provide a clearer picture of your situation. It is advisable to follow up with your healthcare provider or a specialist in urology to explore these avenues further.

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