Weight Gain and Medication Side Effects in Psychiatry - Psychiatry

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Adverse drug reactions, pharmacotherapy, psychiatric medications?


Dr.
Liang: Hello, I apologize for bothering you during your busy schedule.
I am a patient with trichotillomania for over a decade.
I would like to ask about my recent medication change, which has led to a significant increase in my weight, although my appetite has not been particularly good or bad (one might even say it is poor), and I do not have a habit of late-night snacking.
I would like to know if the following three medications could cause weight gain or metabolic issues leading to weight increase: Leeyo F.C.
10mg, Clonopam 0.5mg, and Cardolol 10mg.

Many years ago, when I first encountered psychiatric medications, I became very overweight due to the medication, but after stopping, I lost a significant amount of weight—about ten kilograms within a month.
I am very afraid that this time might be similar, especially since my condition has worsened compared to those years.
Because of this, I am very concerned about my appearance (even though my hair is nearly bald, fortunately, more people are accepting of this hairstyle now, but I still feel anxious about going out, and what worries me more is the weight gain).
My obesity makes me even more afraid to go out, and my hunchback is quite pronounced.
Additionally, since starting the new medications, my mood has become more unstable, and my condition has worsened.
Should I discuss this with my doctor? However, my mother always accompanies me into the consultation room, and I find it difficult to speak up.
If I refuse her, she becomes even more worried.
Over the past decade, I have switched hospitals and clinics, seeing a total of four doctors, and changing medications has become routine.
I previously wanted to see a psychologist (as I had significant improvement with one in the past), but my previous doctor refused, saying that at my age, I did not need one.
The doctor before that agreed to help, but the wait time for a psychologist was very long.
Now, the psychologist at my current clinic requires out-of-pocket payment, which I cannot afford with my current job.

I would like to ask these questions.
I am very sorry for the complicated and bothersome nature of my inquiries.

Nuò mǎ, 20~29 year old female. Ask Date: 2017/05/10

Dr. Liang Sunyuan reply Psychiatry


Hello Norma: Currently, taking these three medications should not cause weight gain.
Weight management is recommended to focus on diet and exercise.
If there are issues with the medication, it is advisable to discuss them with your physician during your follow-up visit.
If you need a private conversation, it would be a good idea to communicate with your mother first; I'm sure she will understand as long as it helps you.
Regarding the psychologist, you can also have a thorough discussion with your physician during your follow-up appointment.
The waiting process does require some patience.
I suggest putting more effort into self-actualization in your daily life.
Wishing you a speedy recovery.

Reply Date: 2017/05/10

More Info


Weight gain as a side effect of psychiatric medications is a common concern among patients, particularly those dealing with conditions such as obsessive-compulsive disorder (OCD), anxiety, and depression. The medications you mentioned—Leeyo F.C. (likely a brand name for an antidepressant), Clonopam (Clonazepam), and Cardolol (a beta-blocker)—can have varying effects on weight, and understanding these effects is crucial for managing your health.

Firstly, it's important to recognize that weight gain can be influenced by multiple factors, including medication, lifestyle, and the underlying condition itself. In your case, you noted that your appetite has not significantly changed, which suggests that the weight gain may not be solely due to increased caloric intake. Instead, it could be related to metabolic changes induced by the medications or the psychological stress associated with your condition.

1. Leeyo F.C.: If this medication is an SSRI (selective serotonin reuptake inhibitor), it is known that some SSRIs can lead to weight gain in certain individuals, particularly with long-term use. However, the initial phase of treatment often sees weight loss due to improved mood and decreased anxiety, which can lead to a more normalized appetite.

2. Clonopam (Clonazepam): This medication is a benzodiazepine used primarily for anxiety and panic disorders. While it is not typically associated with significant weight gain, it can lead to sedation and lethargy, which may reduce physical activity levels and indirectly contribute to weight gain.

3. Cardolol: As a beta-blocker, Cardolol can sometimes lead to weight gain, although this is less common. Beta-blockers can affect metabolism and may lead to fatigue, which can also reduce physical activity.

Given your history of significant weight changes with previous medications, it is understandable that you are concerned about the potential for weight gain with your current regimen. It is essential to communicate these concerns with your healthcare provider. They can assess whether the current medications are appropriate for your condition and discuss alternatives if weight gain becomes a significant issue.

Additionally, the psychological aspect of your situation cannot be overlooked. Anxiety about weight gain can exacerbate your symptoms and lead to a cycle of stress and unhealthy behaviors. It may be beneficial to seek support from a mental health professional, such as a psychologist or counselor, who can help you navigate these feelings. If your current healthcare provider is not supportive of this, consider advocating for your needs or seeking a second opinion.

In terms of managing weight while on psychiatric medications, here are some strategies:
- Regular Exercise: Incorporating physical activity into your routine can help mitigate weight gain. Aim for a mix of cardiovascular and strength-training exercises.

- Balanced Diet: Focus on a diet rich in whole foods, including fruits, vegetables, lean proteins, and whole grains. Monitoring portion sizes can also be helpful.

- Mindfulness and Stress Management: Techniques such as mindfulness meditation, yoga, or deep-breathing exercises can help manage anxiety and reduce stress-related eating.

Lastly, remember that mental health is a priority, and finding the right balance between managing your psychiatric condition and maintaining a healthy weight is crucial. Open communication with your healthcare team is key to achieving this balance. If you feel uncomfortable discussing these issues in front of your mother, consider writing down your concerns or requesting a private consultation with your doctor. Your health and well-being should always come first.

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