PCOS: Managing Weight and Medication Concerns - Obstetrics and Gynecology

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Polycystic Ovary Syndrome (PCOS)


Hello, doctor.
I went to the hospital for an examination yesterday, and I was diagnosed with polycystic ovary syndrome (PCOS).
The doctor didn't say much, but when I asked if medication would help, he said it would.
I also asked my teacher, who mentioned that this condition is quite common and that weight loss is crucial.
However, the medication prescribed to me is Diane (Diane-35), which I found online can lead to weight gain.
Since PCOS can also cause weight gain, it seems contradictory that I need to lose weight while taking a medication that might make me gain weight.
It's possible that the weight I gain from the medication could exceed the weight I lose through exercise, leaving me still overweight.
Will my PCOS persist in that case? If I don't take the medication, go to bed before 11 PM, and exercise daily to lose weight, will my PCOS gradually improve? I hope to avoid further weight gain.
Is that a viable option? I found online that the medication could potentially cause a weight gain of 10 to 20 kilograms.
The reason I visited the gynecologist was that my menstrual cycle has been irregular, with periods occurring twice in one month.
I had my period from April 4 to April 10, then again from April 19 to April 25, and then again from May 5 to May 11, which prompted me to see a doctor.
I didn't expect to be diagnosed with PCOS, and I hope you can help me with my concerns.

Rong, 10~19 year old female. Ask Date: 2017/05/13

Dr. Yang Wangjun reply Obstetrics and Gynecology


Hello: The etiology of Polycystic Ovary Syndrome (PCOS) is not well understood, but it may involve disruptions in pituitary hormones, along with abnormalities in the secretion of ovarian hormones, adrenal hormones, and adipose tissue hormones.
The three main symptoms of PCOS are obesity, ovulatory dysfunction leading to infertility, and elevated androgen levels causing hirsutism, deepening of the voice, and rough skin.
Due to the unclear etiology, treatment typically focuses on symptom management.
The contraceptive pill Diane contains cyproterone acetate, which has anti-androgenic effects and is used for the purpose of treating masculinization.
As for obesity, it may be just one of the symptoms of the condition, but it can also contribute to the development of PCOS.
Weight loss should improve ovulation and menstrual cycle regularity.
Thank you for your inquiry!

Reply Date: 2017/05/13

More Info


Polycystic Ovary Syndrome (PCOS) is a common hormonal disorder that affects women of reproductive age. It is characterized by a combination of symptoms, including irregular menstrual cycles, excess androgen levels (which can lead to symptoms like acne and excessive hair growth), and polycystic ovaries. Managing PCOS can be challenging, especially when it comes to weight management and medication concerns.

Firstly, it’s important to understand that weight management is a crucial aspect of managing PCOS. Many women with PCOS struggle with weight gain or have difficulty losing weight due to insulin resistance, which is common in this condition. Insulin resistance can lead to higher insulin levels, which can promote weight gain and exacerbate other symptoms of PCOS. Therefore, weight loss can help improve insulin sensitivity, regulate menstrual cycles, and reduce the risk of developing other health issues such as type 2 diabetes and cardiovascular disease.

Regarding the medication you mentioned, Diane (often referred to as Diane-35), it is a combination of estrogen and progestin that is commonly prescribed to manage symptoms of PCOS, particularly to regulate menstrual cycles and reduce androgen levels. While some women may experience weight gain as a side effect of hormonal contraceptives, the impact varies from person to person. It’s important to discuss your concerns with your healthcare provider, as they can help you weigh the benefits of the medication against the potential side effects.

You raised a valid concern about the potential for weight gain from the medication while also needing to lose weight to manage PCOS. This can indeed feel contradictory. However, it’s essential to approach this holistically. Here are some strategies to consider:
1. Diet and Nutrition: Focus on a balanced diet that is low in refined carbohydrates and high in fiber. Foods such as whole grains, fruits, vegetables, lean proteins, and healthy fats can help manage insulin levels and support weight loss. Keeping a food diary may help you stay accountable and identify any patterns in your eating habits.

2. Regular Exercise: Incorporating both aerobic and strength-training exercises can be beneficial. Aim for at least 150 minutes of moderate-intensity exercise each week. Exercise not only helps with weight management but also improves insulin sensitivity and overall well-being.

3. Sleep Hygiene: Prioritizing good sleep habits is crucial. Aim for 7-9 hours of quality sleep per night. Poor sleep can negatively affect hormones related to appetite and metabolism, making weight management more difficult.

4. Stress Management: High stress levels can exacerbate PCOS symptoms. Consider incorporating stress-reducing activities such as yoga, meditation, or mindfulness practices into your routine.

5. Regular Monitoring: Keep track of your menstrual cycles and any changes in your symptoms. Regular follow-ups with your healthcare provider can help monitor your condition and adjust your treatment plan as necessary.

6. Open Communication with Your Doctor: It’s essential to have an open dialogue with your healthcare provider about your concerns regarding medication and weight gain. If you feel that Diane is not the right fit for you due to potential weight gain, discuss alternative treatment options that may be available.

In conclusion, while managing PCOS can be complex, especially with the interplay of weight management and medication, it is possible to find a balance that works for you. By focusing on lifestyle changes, maintaining open communication with your healthcare provider, and being proactive about your health, you can effectively manage your PCOS symptoms and work towards your health goals. Remember, every individual’s experience with PCOS is unique, and what works for one person may not work for another, so it’s important to find a personalized approach that suits your needs.

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