Ankle Pain: Can Cartilage Regenerate After OCD Diagnosis? - Orthopedics

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Ankle pain


If a doctor diagnoses OCD (Osteochondritis Dissecans) and indicates instability and pain, it may suggest the need for surgery.
However, regarding cartilage wear, the question arises whether cartilage can regenerate or if artificial options are available.
Thank you.

Qiu Da B, 40~49 year old female. Ask Date: 2017/05/23

Dr. Shi Guozheng reply Orthopedics


Cartilage typically does not regenerate, and the durability of artificial ankle joints is not very good, so there are not many people who undergo this procedure.

Reply Date: 2017/05/23

More Info


Osteochondritis dissecans (OCD) is a condition that affects the cartilage and underlying bone in joints, most commonly the knee and ankle. When a physician diagnoses OCD, particularly if it is unstable and causing pain, surgical intervention is often considered. The primary concern with OCD is that the affected cartilage can become loose or detached, leading to joint pain and dysfunction.

Regarding your question about cartilage regeneration, it is important to understand that cartilage has a limited ability to heal itself. Unlike other tissues in the body, cartilage does not have a direct blood supply, which significantly hampers its ability to regenerate after injury. When cartilage is damaged, the body’s natural healing processes are often insufficient to restore it to its original state.
In cases of OCD, if the cartilage is stable and the lesion is small, conservative treatment options such as rest, physical therapy, and anti-inflammatory medications may be effective. However, if the OCD lesion is unstable, surgical options become necessary. The type of surgery performed can vary depending on the severity of the condition and the specific characteristics of the lesion.

1. Microfracture Surgery: This technique involves creating small holes in the bone beneath the damaged cartilage. This procedure stimulates the body to produce new cartilage, but the new cartilage is often fibrocartilage, which is not as durable as the original hyaline cartilage.

2. Osteochondral Autograft Transplantation: In this procedure, healthy cartilage and bone are taken from another part of the patient’s joint and transplanted to the area of the OCD lesion. This method can provide a more durable solution, as it uses the patient’s own tissue.

3. Allograft Transplantation: If the defect is large, a donor graft may be used. This involves transplanting cartilage and bone from a deceased donor. This option can be effective but comes with the risk of rejection and other complications.

4. Cartilage Regeneration Techniques: There are newer techniques, such as autologous chondrocyte implantation (ACI), where cartilage cells are harvested, cultured, and then re-implanted into the damaged area. This method aims to regenerate hyaline cartilage, but it is more complex and requires a longer recovery period.

In summary, while cartilage has limited regenerative capabilities, there are surgical options available that can help restore function and alleviate pain associated with OCD. If your physician has indicated that surgery is necessary due to instability and pain, it is likely because they believe that the benefits of surgical intervention outweigh the risks. It is essential to have a thorough discussion with your orthopedic surgeon about the specific surgical options available, the expected outcomes, and the rehabilitation process following surgery. This will help you make an informed decision about your treatment plan and set realistic expectations for recovery.

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