Knee Cartilage Damage: Healing and Treatment Options - Orthopedics

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Knee cartilage defect issue?


Hello, doctor.
Three months ago, I experienced pain in my left knee after overstretching my ankle while pumping at home.
I can walk on flat surfaces without pain, but going up and down stairs is extremely painful.
I can only walk in places with ramps.
After an MRI, the doctor informed me that there is a hole in the cartilage behind my patella, which is somewhat deep.
This causes friction between the bones when my knee bends, resulting in pain.
Will the pain go away once the cartilage hole heals over time? I have consulted two hospitals; one said that the damaged cartilage will not regenerate, while the other said it might heal slowly but without guarantees.
I can avoid activities like going up and down stairs and squatting.
I haven't taken the anti-inflammatory pain medication prescribed by the doctor (since I don't feel pain on flat surfaces, I prefer not to take it).
I do leg raises in bed 100 times daily to strengthen my quadriceps.
I take glucosamine twice a day.
I considered PRP injections, but the doctor mentioned that it may not be effective for everyone.
If I opt for hyaluronic acid injections, it seems impractical to do that for a lifetime.
Additionally, I am apprehensive about undergoing another surgery since I had ankle fracture surgery five months ago.
Could you please advise me on what I should do now? Am I really destined to live with this pain for life? Will the hole gradually repair itself, or will it worsen and lead to osteoarthritis? Thank you.

Nìmíng, 30~39 year old female. Ask Date: 2021/03/11

Dr. Shi Guozheng reply Orthopedics


Continue taking medication and undergoing rehabilitation; if that doesn't work, we can consider trying PRP (Platelet-Rich Plasma) therapy.

Reply Date: 2021/03/11

More Info


Knee cartilage damage, particularly in the context of a defect or "hole" in the cartilage, can be a significant source of discomfort and functional limitation. Based on your description, it seems that you have a cartilage defect on the posterior aspect of your patella (kneecap), which is causing pain during activities that involve bending the knee, such as climbing stairs.
To address your concerns, let's break down the situation and explore the healing process, treatment options, and what you can do to manage your symptoms.


Understanding Cartilage Healing
Cartilage is a unique tissue that has limited regenerative capabilities. When a cartilage defect occurs, the body does not typically heal it in the same way that it would heal a bone fracture. Instead, the body may form a type of scar tissue known as fibrocartilage, which is not as durable or functional as the original hyaline cartilage.
1. Will the cartilage hole heal on its own?
- The consensus among orthopedic specialists is that small defects may partially heal over time, but larger defects, especially those that are deep, are less likely to heal completely. The healing process can be influenced by various factors, including the size and location of the defect, your age, activity level, and overall health.

2. Will the defect lead to osteoarthritis?
- Yes, if the cartilage defect is significant and leads to bone-on-bone contact, it can increase the risk of developing osteoarthritis in the knee joint over time. The friction caused by the defect can lead to further cartilage wear and joint degeneration.


Treatment Options
Given your situation, here are some treatment options and strategies to consider:
1. Physical Therapy:
- Continuing with physical therapy is crucial. Strengthening the quadriceps and surrounding muscles can help stabilize the knee joint and reduce pain. Focus on low-impact exercises that do not exacerbate your symptoms.
2. Activity Modification:
- As you mentioned, avoiding activities that cause pain, such as climbing stairs or squatting, is wise. Instead, seek out flat surfaces or ramps when walking.

3. Medications:
- While you have not taken the anti-inflammatory medication prescribed, it may be beneficial to consider it during flare-ups of pain. Discuss with your doctor about alternatives if you have concerns about side effects.

4. Injections:
- PRP (Platelet-Rich Plasma): This treatment involves injecting your own platelets into the knee to promote healing. While results can vary, some patients report improvement in pain and function.

- Hyaluronic Acid Injections: These can provide lubrication to the joint and may help alleviate pain. However, as you noted, this may not be a long-term solution.

5. Surgical Options:
- If conservative treatments fail and your pain persists, surgical options may be considered. These can include:
- Microfracture: A procedure that creates small holes in the bone beneath the cartilage to stimulate healing.

- Osteochondral Autograft Transplantation: This involves taking healthy cartilage from another part of your knee and transplanting it to the damaged area.

- Cartilage Regeneration Techniques: Such as stem cell therapy, though these are still under research and not universally available.


Conclusion
It is understandable to be concerned about the long-term implications of your knee cartilage damage. While the defect may not heal completely, many individuals can manage their symptoms effectively through a combination of physical therapy, activity modification, and possibly injections. It is essential to maintain open communication with your orthopedic specialist to monitor your condition and adjust your treatment plan as necessary.

In summary, while the cartilage may not regenerate fully, there are numerous strategies to manage your symptoms and maintain a good quality of life. Regular follow-ups with your healthcare provider will help ensure that you are on the best path for recovery.

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