Innovative Treatments for Knee Cartilage Damage: What’s New? - Orthopedics

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Knee cartilage degeneration?


When I was 16 years old, I had a motorcycle accident that injured the cartilage in both of my knees.
At that time, the doctor performed an arthroscopy and said it was a permanent injury, advising me to avoid any intense physical activities (except swimming).
I would like to know if there are any new technologies or treatments available now, given the advancements in medicine.
I currently experience soreness after squatting for just ten minutes, and my knees become painful when it's cold while riding a bike.
I really regret riding fast.
I would appreciate your response.
Thank you.

A De, 20~29 year old female. Ask Date: 2005/02/23

Dr. Shi Guozheng reply Orthopedics


The cartilage in your patella has issues, and currently, there are no specific treatments available.
However, rehabilitation may provide some benefits.
Additionally, using glucosamine may help prevent further cartilage degeneration.
Since your patella was not fractured after the injury, it should not be too serious.
Therefore, you should consult a physician for further evaluation, as there may be other solutions available.

Reply Date: 2005/02/23

More Info


Knee cartilage damage is a significant concern, especially for young individuals who have experienced injuries, such as in your case from a motorcycle accident at the age of 16. The fact that your doctor indicated it was a permanent injury and advised against vigorous activities is a common approach when dealing with cartilage damage, as the knee joint is crucial for mobility and stability.

In recent years, advancements in medical technology and treatment options have emerged, offering hope for individuals with knee cartilage damage. Here are some innovative treatments and approaches that have been developed:
1. Regenerative Medicine: This field includes therapies that aim to repair or regenerate damaged tissues. Techniques such as Platelet-Rich Plasma (PRP) therapy involve drawing a small amount of your blood, processing it to concentrate the platelets, and injecting it back into the knee joint. The growth factors in the platelets can promote healing and potentially improve cartilage repair.

2. Stem Cell Therapy: Stem cells have the potential to differentiate into various types of cells, including cartilage cells. Injections of stem cells derived from bone marrow or adipose (fat) tissue are being explored as a way to regenerate damaged cartilage. While still considered experimental, some studies have shown promising results in improving knee function and reducing pain.

3. Microfracture Surgery: This minimally invasive procedure involves creating tiny fractures in the underlying bone to stimulate the growth of new cartilage. The body responds by forming a fibrocartilage layer, which can help alleviate pain and improve function, although it may not be as durable as the original cartilage.

4. Osteochondral Autograft Transplantation: This technique involves taking healthy cartilage and bone from another part of the knee (autograft) and transplanting it to the damaged area. This can be effective for localized cartilage defects but requires a healthy donor site.

5. Synthetic Cartilage Implants: Researchers are developing synthetic materials that can mimic the properties of natural cartilage. These implants can be used to replace damaged cartilage and may provide a longer-lasting solution compared to other methods.

6. Biologic Scaffolds: These are materials that can be implanted into the knee joint to provide a structure for new cartilage to grow. They can be combined with stem cells or growth factors to enhance healing.

7. New Medications: Ongoing research is exploring new drugs that can help manage pain and inflammation associated with cartilage damage. Some of these medications aim to slow the progression of cartilage degeneration.

8. Physical Therapy and Rehabilitation: While not a direct treatment for cartilage damage, a well-structured rehabilitation program can strengthen the muscles around the knee, improve stability, and enhance overall function. Techniques such as aquatic therapy, strength training, and flexibility exercises can be beneficial.

It is essential to consult with an orthopedic specialist who can evaluate your specific condition and recommend the most appropriate treatment options based on the severity of your cartilage damage and your lifestyle. They can also provide guidance on activity modifications and rehabilitation strategies to help manage your symptoms effectively.

In summary, while there may not be a definitive cure for cartilage damage, many innovative treatments are available that can help improve function and reduce pain. Staying informed about these advancements and working closely with your healthcare provider can lead to better outcomes and an improved quality of life.

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