Could It Be Kawasaki Disease? Symptoms in Young Children - Pediatrics

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Could it be Kawasaki disease?


Hello doctor, my daughter is currently one and a half years old.
She started having a fever on May 29 and visited the clinic twice.
On June 1, I noticed she was a bit wheezy, so we went to the emergency room where she had blood tests and an X-ray; the blood test results were normal.
During her hospitalization on June 1, she also had a fever for about 5-6 days and experienced diarrhea.
The doctor diagnosed her with respiratory syncytial virus (RSV).
I would like to know if stating that her fever started on May 31 instead of May 29 when we went to the emergency room would affect the doctor's diagnosis.
Is it possible that having a fever for 6 days could indicate Kawasaki disease? She does not have red eyes or a rash.

Mr. Shi, 30~39 year old female. Ask Date: 2017/06/13

Dr. Xiao Kaiwen reply Pediatrics


Kawasaki disease has diagnostic criteria: (1) fever lasting more than five days; (2) bilateral conjunctival injection without discharge; (3) oral mucosal changes, including bright red, cracked lips and a strawberry tongue; (4) redness and swelling of the palms and soles; (5) non-purulent unilateral cervical lymphadenopathy; (6) polymorphous rash on the trunk.
Therefore, it is likely not Kawasaki disease.
Blood tests and X-ray examinations have been performed, so they should not affect the physician's diagnosis.

Reply Date: 2017/06/13

More Info


Kawasaki disease is a serious condition that primarily affects children, particularly those under the age of five. It is characterized by prolonged fever, rash, conjunctivitis (red eyes), swollen lymph nodes, and changes in the lips and mouth, such as a "strawberry tongue." The exact cause of Kawasaki disease is still unknown, but it is believed to involve an abnormal immune response to an infection or environmental factors.

In your daughter's case, the symptoms you described—fever lasting for 5-6 days, along with respiratory issues and diarrhea—could be indicative of a viral infection, such as the respiratory syncytial virus (RSV), which is common in young children. The fact that her blood tests came back normal is reassuring, as Kawasaki disease often presents with elevated inflammatory markers.
Regarding your question about whether the timing of the fever onset (noting that it was reported as starting on May 31 instead of May 29) could affect the diagnosis, it is important to understand that Kawasaki disease is diagnosed based on a combination of clinical criteria and the duration of fever. The standard diagnostic criteria require a fever lasting more than five days along with at least four of the five principal symptoms. If the fever was indeed present for six days, it could raise suspicion for Kawasaki disease, but the absence of other symptoms such as conjunctivitis, rash, or swollen lymph nodes makes it less likely.

Kawasaki disease can lead to serious complications, particularly involving the heart, such as coronary artery aneurysms. Therefore, if there is any concern about Kawasaki disease, it is crucial to consult with a pediatrician or a pediatric cardiologist for further evaluation. They may recommend an echocardiogram to assess the heart's condition.

In summary, while your daughter's prolonged fever is concerning, the absence of other classic Kawasaki symptoms makes it less likely to be the cause. It is essential to continue monitoring her symptoms and maintain open communication with her healthcare providers. If her condition worsens or if new symptoms arise, do not hesitate to seek further medical attention. Early diagnosis and treatment are key to managing Kawasaki disease effectively, should it be diagnosed.

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