Understanding D-Dimer and Eosinophil Levels in Pediatric Bruising
D-dimer blood test & abnormal eosinophil count? A 5-year-old child has been experiencing spontaneous bruising of various sizes (on the calves, knees, inner thighs, arms, face, and even eyelids) since mid-March. After blood tests conducted by a hematologist, no abnormalities w...
Dr. Ma Zhihao Reply:
If there are suspected petechiae, it is important to have a physician evaluate them first. If the petechiae and bruising continue to appear, it is advisable to check for coagulation function, coagulation factors, platelet levels, and any abnormalities related to autoimmune condit...[Read More] Understanding D-Dimer and Eosinophil Levels in Pediatric Bruising
Using Rebinin in Pediatric ITP: Is Bone Marrow Monitoring Required?
The use of Rebif (interferon beta-1a)? I would like to ask if the standard protocol for administering low-dose Rituximab to children for the treatment of ITP includes the requirement for regular bone marrow aspiration for monitoring.
Dr. Xiao Kaiwen Reply:
The use of intravenous immunoglobulin (IVIG) in the treatment of Immune Thrombocytopenic Purpura (ITP) is considered a later-line therapy, indicating a more complex condition. The chemotherapy protocols in pediatric hematology-oncology are very detailed, cautious, and highly prof...[Read More] Using Rebinin in Pediatric ITP: Is Bone Marrow Monitoring Required?
Understanding ITP and Lymphadenopathy in Pediatric Patients
ITP with lymphadenopathy Hello Doctor, thank you for your prompt response to the previous question <a href="https://adoctor.tw/article/199203">#199203</a>. I would like to provide some additional information. The child in the family has had elevated infectio...
Dr. Xiao Kaiwen Reply:
An elevated CRP (C-reactive protein) level indicates a wide range of possibilities. While the likelihood of infection is highest in children, there are still other potential causes. It is difficult to specify which additional tests should be arranged at this point; however, it is...[Read More] Understanding ITP and Lymphadenopathy in Pediatric Patients
Understanding ITP in Children: Immune System's Role in Low Platelet Counts
Childhood thrombocytopenic purpura (ITP) Hello Doctor: A family member's child has been diagnosed with ITP for a year. Previously, they used Romiplostim, and the platelet count generally ranged between 20,000 to 70,000, with a maximum count reaching 170,000. When using immun...
Dr. Xiao Kaiwen Reply:
The currently accepted reason for Immune Thrombocytopenic Purpura (ITP) is that it is caused by an abnormal immune system, which is why the use of immunosuppressants can be effective. However, the term "immunocompromised" is somewhat vague; during this time, platelet co...[Read More] Understanding ITP in Children: Immune System's Role in Low Platelet Counts
Sirolimus for Treating Pediatric ITP: Case Studies and Insights
Medications for pediatric thrombocytopenic purpura (ITP) include corticosteroids, intravenous immunoglobulin (IVIG), anti-D immunoglobulin, and in some cases, thrombopoietin receptor agonists Is there any case of sirolimus being used in the treatment of thrombocytopenic purpura i...
Dr. Xiao Kaiwen Reply:
Sirolimus is an immunosuppressive medication that can be used for treating pediatric immune thrombocytopenia (ITP) caused by autoimmune antibodies destroying platelets. However, it is generally considered a second-line therapy, typically used after first-line treatments have prov...[Read More] Sirolimus for Treating Pediatric ITP: Case Studies and Insights
Improving Appetite and Preventing Bone Loss in Pediatric Steroid Treatment
Decreased corticosteroid levels can lead to loss of appetite? The family’s daughter is nearly 3 years old and is undergoing treatment for ITP (Immune Thrombocytopenic Purpura) with corticosteroids, which she has been taking for 7 months. Currently, due to a reduction in the corti...
Dr. Xiao Kaiwen Reply:
It is recommended to prepare a variety of meals or consult a nutritionist for alternative food options. Additionally, incorporating higher-calorie pediatric nutritional formulas can be beneficial. Avoid providing snacks with poor nutritional value. Furthermore, you may consult a ...[Read More] Improving Appetite and Preventing Bone Loss in Pediatric Steroid Treatment
Understanding ITP in Toddlers: Low Platelet Counts and Anti-dsDNA Connection
Childhood thrombocytopenic purpura (ITP) Hello Dr. Hsiao: Regarding the previous question <a href="https://adoctor.tw/article/185662">#185662</a>, my family member's daughter is over two years old and has been in a state of extremely low platelet count ...
Dr. Xiao Kaiwen Reply:
Anti-dsDNA is indeed associated with certain autoimmune diseases, most commonly systemic lupus erythematosus (SLE). The levels of anti-dsDNA often correlate clearly with disease activity. However, determining whether there is a connection between your child's thrombocytopeni...[Read More] Understanding ITP in Toddlers: Low Platelet Counts and Anti-dsDNA Connection
Understanding Severe ITP in Toddlers: Treatment Challenges and Options
Pediatric Immune Thrombocytopenic Purpura (ITP) Dear Dr. Hsiao, I would like to inquire about my family member's daughter, who is over 2 years old. She was diagnosed with idiopathic thrombocytopenic purpura (ITP) after being found to have low platelet counts in mid-March. I...
Dr. Xiao Kaiwen Reply:
Most cases of ITP show improvement with high-dose corticosteroids and immunoglobulin treatment. However, there are a few cases where these treatments are not effective, and in such instances, chemotherapy (such as the one you mentioned, possibly referring to rituximab) and more i...[Read More] Understanding Severe ITP in Toddlers: Treatment Challenges and Options
Does Allergic Purpura in Childhood Increase Autoimmune Disease Risk?
Allergic purpura is an autoimmune disease? Hello, doctor. I would like to ask if having had allergic purpura as a child (around fifth grade) makes one more susceptible to other autoimmune diseases later in life, such as multiple sclerosis?
Dr. Xiao Kaiwen Reply:
There is no research indicating that having allergic purpura in childhood increases the likelihood of developing other autoimmune diseases later in life. However, some studies suggest that if a girl has this condition, she may be more likely to experience proteinuria and hyperten...[Read More] Does Allergic Purpura in Childhood Increase Autoimmune Disease Risk?
Is BNT Vaccine Safe for My Son with a History of Allergic Purpura?
Is it suitable for children who have a history of allergic purpura to receive the BNT vaccine? My son is currently in the first year of junior high school and just turned thirteen. He experienced allergic purpura at the age of six, which has not recurred since then. The diagnosin...
Dr. Xiao Kaiwen Reply:
Allergic purpura is an autoimmune vasculitis characterized by inflammation of the blood vessels. The cause of the production of autoimmune antibodies is unknown, but it is speculated that it may be triggered by previous viral infections. However, if there have been no recurrences...[Read More] Is BNT Vaccine Safe for My Son with a History of Allergic Purpura?
Managing Persistent Fever in Toddlers: When to Seek Emergency Care
Pediatric fever Hello, my daughter is currently 1 year and 4 months old. This past Monday morning, she was diagnosed with acute pharyngitis at Clinic A due to a fever. After returning home and taking her medication on schedule, she continued to have recurrent high fevers (between...
Dr. He Zongxian Reply:
Hello, taking care of a feverish child has been really tough these past few days! However, if your daughter continues to have a fever (lasting more than 72 hours) or experiences any of the following symptoms, it is advisable to go to the hospital for further evaluation: a tempera...[Read More] Managing Persistent Fever in Toddlers: When to Seek Emergency Care
Understanding Frequent Bruising on Your Child's Knees: When to Worry
Frequent bruising of the knee? Hello Doctor, my son is seven years old and in second grade. Since the second semester of his first grade, I have noticed that he often has bruises on his knees. We have tested his prothrombin time (PT) which is 10.7 seconds, and activated partial t...
Dr. Xiao Kaiwen Reply:
Coagulation function includes PT, APTT, total platelet count, and platelet function (bleeding time, which seems not to have been tested for your child). If all these tests are normal, there should be no issues with coagulation function or hemophilia. If there are problems with co...[Read More] Understanding Frequent Bruising on Your Child's Knees: When to Worry
Understanding Low Platelet Counts in Children: Causes and Concerns
Low platelet count? Hello, doctor. My child has been hospitalized a few times in the past. In 2018, the platelet counts were normal, with the first hospitalization showing a count of 191 and the second hospitalization showing a count of 163 (both occurred one month apart and were...
Dr. Xiao Kaiwen Reply:
Generally, common illnesses do not cause thrombocytopenia unless they are specific, rare, and severe diseases. A platelet count above 100,000 is considered normal, while thrombocytopenia (purpura) is defined as a platelet count below 20,000. It is important to monitor for any unu...[Read More] Understanding Low Platelet Counts in Children: Causes and Concerns
Understanding Roseola in Children: Causes of Skin Changes After Rash
Regarding roseola? Hello, I would like to ask about my child who is currently 1 year and 3 months old. Two weeks ago, they developed roseola, which started to fade after about 3 to 4 days. However, it seems like there is some pigmentation left, and their skin has developed a spec...
Dr. Pei Rensheng Reply:
Hello: Roseola generally resolves within 2 days; it rarely causes pigmentation similar to measles. A small number of roseola cases may be associated with thrombocytopenic purpura; if pigmentation becomes increasingly noticeable, please return for a follow-up visit and consider bl...[Read More] Understanding Roseola in Children: Causes of Skin Changes After Rash
Understanding Chickenpox in Infants After BCG Vaccination
Infants develop chickenpox? Hello doctor, my son is currently over five months old. He received the BCG vaccine last Friday, and unexpectedly, he developed chickenpox a week later. Is there any conflict between the BCG vaccine and chickenpox in his body? What should I be aware of...
Dr. Xiao Kaiwen Reply:
The BCG vaccine and varicella (chickenpox) do not conflict with each other. Aspirin and other salicylate medications should not be used as antipyretics. Complications of varicella include pneumonia, encephalitis, secondary bacterial infections, and sepsis. Therefore, the dangerou...[Read More] Understanding Chickenpox in Infants After BCG Vaccination
Understanding Mild Fever in Toddlers: Is It Roseola or Just a Cold?
Mild fever Hello, Doctor. My daughter is currently one year and four months old. She suddenly had a fever of 38 degrees Celsius last night. We took her to see a pediatrician, who noted that her throat was slightly red but not serious, and there were no other cold symptoms. We hav...
Dr. Xiao Kaiwen Reply:
If there are no rashes present on the body, it cannot be definitively determined to be roseola; similarly, it cannot be arbitrarily concluded that it is merely a cold. The following symptoms require immediate medical evaluation: persistent high fever lasting more than four days, ...[Read More] Understanding Mild Fever in Toddlers: Is It Roseola or Just a Cold?
Understanding Mucus and Blood in Children's Stool: When to Seek Help
Children may experience the passage of transparent, sticky mucus during bowel movements? I would like to consult a doctor about my 11-year-old son. Since June, he has been experiencing the presence of a transparent, viscous substance in his stool, sometimes accompanied by blood. ...
Dr. Pei Rensheng Reply:
Dear Anna, Regarding red stools, the first step is to confirm whether the color is due to red items (such as ingested foreign objects or the natural color of food). The second consideration is bleeding. Causes of bleeding can include infections, foreign bodies, constipation with...[Read More] Understanding Mucus and Blood in Children's Stool: When to Seek Help
Persistent High Fever in Children: What to Do When It Reaches 39°C?
The child has a persistent fever above 39 degrees Celsius? If a child has a fever over 39 degrees Celsius and a consistently sore throat, and despite seeing a pediatrician and using rectal antipyretics, the condition remains unchanged, what should be done?
Dr. Xiao Kaiwen Reply:
The effects of various antipyretics can only last for a few hours, and their purpose is to provide temporary comfort for children. If the illness is not resolved (common viral infections typically cause fever for three to four days, and some may last up to a week), it is quite co...[Read More] Persistent High Fever in Children: What to Do When It Reaches 39°C?
Chronic Abdominal Pain in Children: Understanding Symptoms and Next Steps
Long-term distress? Hello doctor, I have been experiencing intermittent abdominal pain for over a year. Initially, the pain was only in the lower right abdomen, but it later spread to the lower left abdomen and eventually involved both upper quadrants. I also started to feel a bl...
Dr. Xiao Kaiwen Reply:
Purpura can be evaluated by a rheumatologist or immunologist. However, your concerns are more appropriately addressed by an adult medicine specialist rather than our pediatric department.[Read More] Chronic Abdominal Pain in Children: Understanding Symptoms and Next Steps
Understanding Vasculitis in Children: Concerns and Treatment Options
Vasculitis refers to a group of disorders characterized by inflammation of the blood vessels, which can lead to changes in the vessel wall Hello Doctor: My daughter developed a rash on the sole of her foot at the end of November last year. Initially, we thought it was allergic pu...
Dr. He Ciyuan Reply:
Vasculitis is an inflammation of the blood vessels that can lead to vessel lumen collapse and ischemia. The etiology may involve abnormal immune mechanisms, particularly the deposition of immune complexes. There are many types of vasculitis, and it is unclear which type your chil...[Read More] Understanding Vasculitis in Children: Concerns and Treatment Options