Can vitamin C (1000 mg) be taken simultaneously with the following medications?
Hello, Doctor! I would like to ask if it is safe to take Vitamin C (1000 mg/day) simultaneously with the following medications.
If not, is it acceptable to space them out by 2 to 3 hours? Or should Vitamin C not be taken at all while on these medications?
1.
Aspirin (Bokey) 100 mg/cap
2.
Ezetimibe (Ezetrol) 10 mg/tab
3.
Candesartan (Blopress) 8 mg/tab
4.
Norvasc (Amlodipine) 5 mg/tab
Thank you very much for your kind response!
Zhang Xiansheng, 40~49 year old female. Ask Date: 2017/06/13
Dr. Li Han reply Cardiology
Hello, regarding your question about whether Vitamin C (1000 mg/day) can be taken simultaneously with the following medications: If not taken at the same time, is it acceptable to space them out by 2 to 3 hours? Or should Vitamin C not be taken at all while on these medications? Vitamin C can indeed interact with many medications, but these interactions are generally not severe.
Typically, they may lead to a reduction in the efficacy of Vitamin C itself or interfere with the metabolism of other medications, potentially causing drug accumulation.
The medications you mentioned, Aspirin and Amlodipine, are more likely to be affected.
It is advisable to consult a professional pharmacist or prescribing physician for further guidance.
Changhua Hospital, Ministry of Health and Welfare, cares about your health.
Reply Date: 2017/06/13
More Info
When considering the concurrent use of Vitamin C (ascorbic acid) with heart medications, it is essential to understand both the potential interactions and the pharmacological properties of each medication involved. Vitamin C is a water-soluble vitamin that plays a crucial role in various bodily functions, including collagen synthesis, antioxidant activity, and immune function. However, it can also interact with certain medications, which may affect their efficacy or safety.
Interactions with Specific Medications
1. Aspirin (Bokey) 100 mg/cap: Vitamin C may have a mild interaction with aspirin. Some studies suggest that high doses of Vitamin C can potentially reduce the effectiveness of aspirin in certain contexts, particularly in terms of its anti-inflammatory effects. However, this interaction is not considered clinically significant for most patients. Taking Vitamin C and aspirin together is generally safe, but if you are concerned, spacing them out by a few hours, as you suggested, is a prudent approach.
2. Ezetimibe (Ezetrol) 10 mg/tab: There is no significant evidence to suggest that Vitamin C interacts adversely with ezetimibe. Ezetimibe works by inhibiting the absorption of cholesterol in the intestines, and Vitamin C does not appear to affect this mechanism. Therefore, it is likely safe to take them together.
3. Candesartan (Blopress) 8 mg/tab: Candesartan is an angiotensin II receptor blocker (ARB) used primarily for hypertension and heart failure. There are no known significant interactions between Vitamin C and candesartan. As with the other medications, taking them together should not pose any issues.
4. Norvasc (Amlodipine) 5 mg/tab: Amlodipine is a calcium channel blocker used to treat high blood pressure and angina. Similar to the previous medications, there are no significant interactions reported between Vitamin C and amlodipine. They can typically be taken together without concern.
General Recommendations
- Timing: If you are worried about potential interactions, taking Vitamin C a few hours apart from these medications is a reasonable strategy. This approach can help minimize any theoretical risk of interaction and ensure that each medication can exert its intended effect without interference.
- Dosage: The dosage of 1000 mg of Vitamin C daily is generally considered safe for most individuals. However, excessive Vitamin C intake can lead to gastrointestinal disturbances, such as diarrhea or abdominal cramps, particularly in sensitive individuals.
- Monitoring: It is always advisable to monitor how you feel when starting any new supplement or medication. If you notice any unusual symptoms, such as increased heart rate, chest pain, or gastrointestinal discomfort, it is essential to consult your healthcare provider.
Conclusion
In summary, taking Vitamin C with the medications you listed—aspirin, ezetimibe, candesartan, and amlodipine—is generally considered safe. While there may be minor interactions, they are not typically clinically significant. If you have specific health concerns or underlying conditions, it is always best to discuss them with your healthcare provider or a pharmacist who can provide personalized advice based on your overall health status and medication regimen.
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