Syphilis: One positive, one negative?
Hello Doctor, I was diagnosed with gonorrhea in early June after having unprotected sexual intercourse on May 30.
My gonorrhea has been treated successfully, and my blood test results show that I am HIV negative.
However, for syphilis, I received one positive and one negative result.
Since I do not understand the medical terminology, I did not ask the doctor which result was positive and which was negative.
I had blood drawn during my second follow-up visit after taking the antibiotics and other medications prescribed by the doctor.
My previous test in early April showed negative results for both HIV and syphilis.
After being diagnosed with gonorrhea, I was required to undergo testing, which led to the results mentioned above.
I have the following questions:
1.
Could the antibiotics and pain relievers prescribed by the doctor during the first week have affected the test results?
2.
Are chancroid and hard chancre lesions only located on the penis? (I have a habit of checking my genital area, and I have never noticed any unusual signs, except for a period when I had pubic lice that caused intense itching, and I kept scratching the affected area.)
3.
If I happen to enlist in the military, can syphilis treatment continue?
4.
If I want to get tested anonymously, how long should I wait based on my current results before getting retested?
I would appreciate your answers to these questions.
Thank you!
KK, 20~29 year old female. Ask Date: 2017/06/16
Dr. Du Shixi reply Urology
Hello: 1) It will not affect.
2) Is the location of hard chancre and soft chancre only on the penis? --> Primarily, but they can also occur in the perineum.
Many sexually transmitted infections (STIs) are asymptomatic; just because there are no symptoms does not mean you should be at ease, which is why testing is essential (the blood test you took should check for past STIs, and the unsafe sexual behavior in May may fall within the window period).
3) Yes, after treatment, you will need to have regular blood tests for long-term monitoring (some individuals may have rising levels without symptoms).
4) Please practice safe sexual behavior for the next three months.
Wishing you good health.
Reply Date: 2017/06/16
More Info
Understanding syphilis test results can be quite complex, especially when faced with terms like "reactive" or "positive." In your case, it seems that you have had a reactive test result for syphilis, which typically indicates that the test has detected antibodies against the syphilis-causing bacterium, Treponema pallidum. However, it's crucial to understand that a reactive test does not automatically confirm a syphilis diagnosis; further testing is often required to confirm the presence of the infection.
1. Impact of Antibiotics on Test Results: The antibiotics you were prescribed for gonorrhea treatment may not directly affect the syphilis test results, especially if the syphilis infection was not present at the time of testing. However, if you had an active syphilis infection and were treated with antibiotics, it could potentially lower the antibody levels, leading to a false-negative result in some cases. Generally, the RPR (Rapid Plasma Reagin) test, which is often used for syphilis screening, can yield false positives due to various factors, including recent infections, autoimmune diseases, or even pregnancy. It's essential to follow up with your healthcare provider for clarification on your specific test results.
2. Understanding Chancre Locations: The primary lesion of syphilis, known as a chancre, typically appears at the site of infection, which can be on the genitals, anus, or mouth. In your case, if you have noticed any unusual sores or lesions on your penis, it would be wise to have them evaluated by a healthcare professional. Soft chancre (chancroid) is caused by a different bacterium (Haemophilus ducreyi) and is characterized by painful sores, while hard chancre (primary syphilis) is usually painless. If you have been experiencing itching or irritation, it could be due to other conditions, such as a fungal infection or irritation from lice, rather than syphilis.
3. Continuing Treatment During Military Service: If you are called to military service, it is crucial to inform the medical staff about your syphilis treatment. Syphilis treatment typically involves a course of penicillin, which is highly effective. The military medical staff can coordinate your treatment to ensure that you complete the necessary regimen. It is essential to adhere to the treatment plan to avoid complications and ensure complete resolution of the infection.
4. Timing for Re-testing: If you are considering getting tested again for syphilis after a reactive result, it is generally recommended to wait at least 6 weeks after your last potential exposure or after completing treatment. This allows enough time for your body to produce detectable antibodies if an infection is present. However, if you are experiencing symptoms or have concerns, it is advisable to consult with a healthcare provider sooner.
In summary, a reactive syphilis test indicates that further evaluation is necessary to confirm the diagnosis. It is essential to communicate openly with your healthcare provider about your symptoms, treatment history, and any concerns you may have. They can guide you through the next steps, including confirmatory testing and appropriate treatment if needed. Remember, early detection and treatment of syphilis are crucial to prevent complications and transmission to others.
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