Creatinine Levels and Glomerular Filtration Rate Changes - Internal Medicine

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Understanding creatinine levels and glomerular filtration rate (GFR) is crucial for assessing kidney function. In your case, your creatinine level is 1.05 mg/dL, and your GFR is 83 mL/min, which indicates that your kidney function is somewhat reduced compared to the normal range. Typically, a GFR above 90 mL/min is considered normal, while a GFR between 60-89 mL/min indicates mild kidney impairment.
The decline in your GFR from over 130 mL/min two years ago to 83 mL/min now is significant and could be attributed to several factors. The most common causes of reduced kidney function include chronic conditions such as hypertension and diabetes, both of which can lead to kidney damage over time. Since you have a history of high blood pressure and are on medication for it, this could be a contributing factor to the decline in your kidney function.
It's also important to consider the medications you are taking. While the antihypertensive medication you mentioned (康肯, likely a brand name) is generally safe for kidney function, some medications can have nephrotoxic effects, especially if taken over a long period. Additionally, the use of antiviral medications for herpes could also have implications for kidney health, depending on the specific drug and dosage.
Your daily water intake of 3000-3500 cc is commendable, as adequate hydration is essential for kidney health. However, it's crucial to ensure that your blood pressure remains well-controlled, as uncontrolled hypertension can lead to further kidney damage.
Given the changes in your kidney function, it would be prudent to discuss further testing with your healthcare provider. This could include additional blood tests to monitor kidney function, urine tests to check for protein or other abnormalities, and possibly imaging studies to assess kidney structure. Lifestyle modifications, such as maintaining a healthy diet low in sodium, regular exercise, and managing stress, can also be beneficial for your overall health and kidney function.

In summary, while your current creatinine and GFR levels indicate some degree of kidney impairment, the situation is not uncommon, especially in individuals with a history of hypertension. Regular monitoring and proactive management of your health conditions are essential to prevent further decline in kidney function. Always consult with your healthcare provider for personalized advice and treatment options tailored to your specific health needs.