High Fever After Starting Birth Control Pills: Is It a Side Effect? - Obstetrics and Gynecology

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After starting to take oral contraceptives, experiencing a persistent high fever?


Recently, after my first visit to the obstetrics and gynecology department, I took the oral contraceptive pill (Yueji) for the first time at 8 PM on the fifth day of my menstrual cycle.
The next morning, I experienced cold sweats and chills, but these symptoms did not last long.
After taking the pill for the second time, I developed a persistent high fever by the following evening, along with a feeling of pelvic heaviness and discomfort similar to menstrual cramps.
After visiting the emergency room, no infections were detected, and there was no significant increase in white blood cell count.
The doctor suspected a possible pelvic infection, but my last sexual encounter with my boyfriend was over a week ago, and since the end of my menstrual cycle, I have had no unusual discharge.
However, the pelvic discomfort has persisted for about three to four days.
I would like to know if this could be a side effect of the oral contraceptive pill, or if I should get checked for a pelvic infection.
Thank you very much.

Stella, 20~29 year old female. Ask Date: 2017/07/16

Dr. Huang Yiwen reply Obstetrics and Gynecology


Hello Miss Stella: Your condition and symptoms are more likely indicative of acute pelvic inflammatory disease.
The most common side effects of oral contraceptives are nausea, vomiting, and gastrointestinal discomfort.
Since you have already seen a doctor, I recommend that you observe your symptoms for a few more days.

Reply Date: 2017/07/16

More Info


When it comes to starting birth control pills, particularly hormonal contraceptives like the one you mentioned (悦己), it is not uncommon for some women to experience side effects, including changes in body temperature and other symptoms. However, a high fever is not a typical side effect of birth control pills.
The symptoms you described, such as chills, cold sweats, and pelvic discomfort, could be indicative of several different conditions. While hormonal contraceptives can cause side effects like nausea, headaches, and mood changes, a persistent high fever and pelvic pain warrant further investigation. It is essential to consider that the onset of these symptoms shortly after starting the pill may not be directly related to the medication itself but could be coincidental.

In your case, the high fever and pelvic discomfort could suggest a possible infection, such as pelvic inflammatory disease (PID), especially if there was any recent sexual activity. PID can occur when sexually transmitted bacteria spread from the vagina to the uterus, fallopian tubes, or ovaries. Symptoms often include fever, unusual discharge, and pelvic pain. However, since you mentioned that you had not engaged in sexual activity for over a week and had no unusual discharge, the likelihood of PID may be lower, but it cannot be completely ruled out.

Given that your white blood cell count was normal and no clear infection was identified during your emergency visit, it is still advisable to follow up with your healthcare provider. They may recommend further testing, such as a pelvic exam, ultrasound, or additional blood tests, to rule out any underlying issues.
It is also worth noting that some women may experience a temporary adjustment period when starting hormonal contraceptives, which can include changes in menstrual cycle patterns, mood swings, and physical discomfort. However, these symptoms typically do not include high fever. If your symptoms persist or worsen, it is crucial to seek medical attention promptly.

In summary, while hormonal contraceptives can lead to various side effects, a high fever is not a common one. Your symptoms could be indicative of an infection or another medical condition that requires further evaluation. It is essential to communicate openly with your healthcare provider about your symptoms and concerns to ensure appropriate care and management.

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