the Use of Wart Cream for Genital Warts: A Patient's Inquiry - Urology

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Hello Doctor: I have noticed that there are two to three small white bumps on both sides of the gap at the junction of the glans of my penis.
I went to the hospital for a diagnosis, and the doctor suspected it might be genital warts (since the size is currently small).
They prescribed me a topical medication called Condylox, which I used for the first time (applying it twice a day for three days and then resting for four days).
However, instead of scabbing and falling off, the skin in the treated area appears to be atrophied and wrinkled.
Is this normal? Please help me with this question.

Xiao Huang, 20~29 year old female. Ask Date: 2017/07/16

Dr. Liu Mingyue reply Urology


Small white bumps near the glans, commonly known as pearly penile papules, can sometimes be confused with warts.
It is advisable to consult a urologist for a proper diagnosis.

Reply Date: 2017/07/16

More Info


Dear Patient,
Thank you for your inquiry regarding the use of wart cream for genital warts, specifically the medication you have been prescribed, which is likely a topical treatment such as "克疣寧" (likely referring to a product containing imiquimod or similar active ingredients). It’s understandable to have concerns about the treatment process, especially when dealing with sensitive areas such as the genital region.

Genital warts, caused by certain strains of the human papillomavirus (HPV), can indeed present as small, raised bumps that may appear white or flesh-colored. The treatment you are using is designed to help your immune system recognize and fight the virus, leading to the eventual removal of the warts. However, it is important to note that the response to treatment can vary significantly from person to person.

Regarding your observation of skin atrophy or wrinkling in the treated area, this can occur as a side effect of topical treatments, particularly those that stimulate the immune response or cause localized irritation. The skin in the genital area is particularly sensitive, and reactions can manifest differently than in other areas of the body. Here are a few points to consider:
1. Normal Reaction: Some degree of skin irritation, including atrophy or changes in texture, can be a normal reaction to wart treatments. However, if the skin appears excessively thin, painful, or shows signs of infection (such as increased redness, swelling, or discharge), it is crucial to consult your healthcare provider.

2. Treatment Regimen: The regimen you mentioned—applying the cream twice daily for three days followed by a four-day break—is a common approach. It allows the skin to recover between applications. If you do not see improvement after a few cycles of this regimen, or if the symptoms worsen, it may be necessary to reassess the treatment plan with your doctor.

3. Expectations: It’s important to have realistic expectations regarding the treatment timeline. While some patients may see results quickly, others may take longer to respond. The goal is for the warts to gradually shrink and eventually fall off, which can take several weeks or even months.

4. Follow-Up: If you have concerns about the appearance of the treated area or if the warts do not improve, I recommend scheduling a follow-up appointment with your healthcare provider. They can evaluate the treatment's effectiveness and determine whether an alternative approach is necessary.

5. Additional Treatments: In some cases, additional treatments may be recommended, such as cryotherapy (freezing the warts), laser therapy, or other topical agents. Your healthcare provider will be able to guide you based on your specific situation.

In summary, while some skin changes can be expected with wart treatment, it is essential to monitor the area for any signs of complications. If you have any doubts or if the condition does not improve, please reach out to your healthcare provider for further evaluation and guidance. Your health and comfort are paramount, and there are various options available to manage genital warts effectively.

Best wishes for your recovery, and do not hesitate to seek further assistance if needed.

Sincerely,
Doctor Q&A Teams

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