Diabetes: Key Questions About Diagnosis and Management - Internal Medicine

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Diabetes concerns?


Hello Doctor: My son is 26 years old and has been attracting ants with his urine.
He went to the clinic for a blood test, which showed a fasting blood glucose level of 266 mg/dL and a hemoglobin A1c of 10.58%.
There is a family history of diabetes (both of my parents have diabetes).
Can he be diagnosed with diabetes based on these results? Does he need to start medication? If he controls his diet and exercises regularly, is there a possibility of returning to normal levels? Thank you for taking the time to answer!

Wang Su-Zhen, 40~49 year old female. Ask Date: 2017/08/01

Dr. Xiao Yongxun reply Internal Medicine


Dear Miss Wang Su-Chen:
1.
According to the diagnostic criteria for diabetes set by the American Diabetes Association, a.
a fasting plasma glucose level ≥126 mg/dL after fasting for more than 8 hours, b.
a 2-hour plasma glucose level ≥200 mg/dL during an oral glucose tolerance test, c.
an HbA1c ≥6.5% (with no disproportionate hyperglycemia and using a testing method that meets the international certification standards of NGSP and DCCT), any of the above a, b, or c must be confirmed by two separate tests.
d.
If there are clinical symptoms of diabetes (such as polyuria, polydipsia, polyphagia, and weight loss), a single plasma glucose level ≥200 mg/dL is sufficient for diagnosis.
Therefore, based on the information you provided, it is possible that your son may be diagnosed with diabetes.
Of course, the attending physician will make a definitive diagnosis based on other clinical presentations and physical examinations.
2.
The prevention or management of diabetes primarily involves dietary control and regular exercise; medication is only necessary when required.
Dietary control includes eating until 80% full, avoiding eating too quickly or overeating, and steering clear of high-sugar, high-fat, and high-calorie foods or beverages, as well as instant coffee mixes, cakes, and fried foods.
Dinner should not be too heavy, and moderate activity should be undertaken after meals before going to bed.
Regular exercise is equally important, with a recommendation of at least three times a week for about an hour each session; otherwise, at a minimum, one should take a walk after meals and avoid sitting down to work immediately.
Additionally, ensuring adequate sleep and reducing life stress can also help in blood sugar control.
However, the importance of medication should not be overlooked.
Particularly when blood sugar levels are very high or poorly controlled, relying solely on dietary control and regular exercise is unlikely to yield ideal results; medication will then be necessary to prevent complications such as hyperglycemic ketoacidosis or hyperglycemic hyperosmolar state, which can lead to severe acute complications and pose a risk to life.
Therefore, diet, exercise, and medication remain the primary methods for diabetes management.
3.
Risk factors for developing diabetes include a family history of diabetes, obesity, hypertension, dyslipidemia, lack of exercise, overeating, alcohol abuse, use of certain medications, poor lifestyle choices, and excessive stress.
Moderating diet and engaging in regular exercise can indeed effectively lower blood sugar levels; in some cases, individuals may even restore normal blood sugar levels.
However, practical challenges often arise.
For instance, a family history of diabetes cannot be changed.
Weight loss is difficult and often hard to maintain.
Long-standing habits of eating too quickly, overeating, or excessive drinking in adulthood are also challenging to correct.
The modern sedentary work lifestyle is difficult to change.
While regular exercise may be feasible in the short term, maintaining a good exercise habit for a lifetime is not so easy.
On the other hand, the development of type 2 diabetes does not occur overnight; it often develops gradually over time.
Once symptoms appear, it usually indicates that there are issues with insulin secretion or insulin receptor sensitivity in the body; in other words, maintaining stable blood sugar levels becomes challenging.
Therefore, dietary moderation and regular exercise can potentially restore normalcy; however, long-term medication management is often safer.
4.
Please ensure that your son discusses his condition and challenges thoroughly with his attending physician to collaboratively make informed decisions, as this is the best approach to finding solutions.

Reply Date: 2017/08/01

More Info


Based on the information provided, it appears that your son has been diagnosed with diabetes, given his fasting blood glucose level of 266 mg/dL and an HbA1c of 10.58%. According to the American Diabetes Association (ADA) guidelines, a fasting blood glucose level of 126 mg/dL or higher, or an HbA1c of 6.5% or higher, indicates diabetes. Since both of your son's results exceed these thresholds, he can indeed be classified as having diabetes.


Diagnosis and Initial Management
Given the significant elevation in blood glucose levels, it is crucial for your son to consult with a healthcare provider, preferably an endocrinologist, to discuss the best management plan. In many cases, lifestyle changes such as dietary modifications and increased physical activity are essential first steps in managing diabetes. However, due to the high levels of glucose in his blood, medication may also be necessary to help control his blood sugar levels effectively.


Medication Considerations
The decision to start medication will depend on several factors, including his overall health, the presence of any diabetes-related complications, and how well he can manage his blood sugar levels through diet and exercise alone. Common medications for type 2 diabetes include metformin, which helps improve insulin sensitivity and lower blood sugar levels. In some cases, if blood sugar levels remain high despite lifestyle changes, additional medications or insulin therapy may be required.


Lifestyle Modifications
1. Dietary Changes: A balanced diet is crucial for managing diabetes. Your son should focus on:
- Reducing intake of refined carbohydrates and sugars (e.g., white bread, pastries, sugary drinks).

- Increasing fiber intake through whole grains, fruits, vegetables, and legumes.

- Monitoring portion sizes to avoid overeating.

- Considering a meal plan that includes regular, balanced meals to help maintain stable blood sugar levels.

2. Physical Activity: Regular exercise can significantly improve insulin sensitivity and help lower blood sugar levels. The ADA recommends at least 150 minutes of moderate-intensity aerobic activity per week, such as brisk walking, swimming, or cycling. Additionally, incorporating strength training exercises at least twice a week can be beneficial.

3. Weight Management: If your son is overweight, losing even a small percentage of body weight can improve blood sugar control and reduce the risk of diabetes-related complications.


Monitoring and Follow-Up
Regular monitoring of blood glucose levels is essential for managing diabetes. Your son should work with his healthcare provider to establish a schedule for checking his blood sugar and follow up on his HbA1c levels every three to six months to assess how well his management plan is working.


Potential for Reversal
While type 2 diabetes is often considered a chronic condition, there is evidence that with significant lifestyle changes, some individuals can achieve remission, meaning their blood sugar levels return to normal without the need for medication. This typically requires sustained weight loss, dietary changes, and regular physical activity. However, it is essential to approach this goal with realistic expectations and under medical supervision.


Conclusion
In summary, your son has likely been diagnosed with diabetes based on his blood test results. It is crucial for him to consult with a healthcare provider to discuss medication options and develop a comprehensive management plan that includes dietary changes and regular exercise. With dedication and the right support, there is potential for improvement in his condition, and he may even achieve normal blood sugar levels over time.

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