HPV Vaccination for Men: Urology Insights and Recommendations - Urology

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Human Papillomavirus Vaccine


Hello, Doctor.
I would like to ask about the HPV vaccine.

1.
If a male wants to receive the HPV vaccine, should he consult a urologist or a gynecologist?
2.
If he is to receive the vaccine, is it the quadrivalent vaccine? Recently, there seems to be a nine-valent vaccine available; which one is more recommended for males?
3.
Is there an age limit for receiving this vaccine, especially for males? I have come across some statements online suggesting that "it's better to get vaccinated between X and Y years old," which raises my concern.
Thank you for taking the time to answer my questions.

Niming, 20~29 year old female. Ask Date: 2017/08/27

Dr. Du Shixi reply Urology


Hello: You can refer to http://www.fda.gov.tw/mlms/H0001D.aspx?Type=Lic&LicId=60001001.
Currently, this type of HPV vaccine has not been approved by the government for use in males.
GARDASIL 9 is a vaccine suitable for girls and women aged 9 to 26, which can be used to prevent lesions caused by human papillomavirus (HPV) including: • Cervical cancer caused by HPV types 16, 18, 31, 33, 45, 52, and 58 • Genital warts (condylomata acuminata) caused by HPV types 6 and 11 • Cervical intraepithelial neoplasia (CIN) grade 1, grade 2, and grade 3 caused by HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 • Adenocarcinoma in situ (AIS) of the cervix, grade 2 and grade 3 vulvar intraepithelial neoplasia (VIN 2/3), and grade 2 and grade 3 vaginal intraepithelial neoplasia (VaIN 2/3) There are no personal objections; however, there have been cases of side effects reported in Japan as well.

Reply Date: 2017/08/27

More Info


When it comes to understanding HPV vaccination for men, it's essential to recognize the significance of HPV (Human Papillomavirus) and its potential health implications. HPV is a common sexually transmitted infection that can lead to various health issues, including genital warts and certain types of cancer, such as anal, penile, and oropharyngeal cancers. While much of the focus has historically been on women and cervical cancer, men are also at risk and should be aware of HPV and the benefits of vaccination.

1. Where to Get Vaccinated: If a man wishes to receive the HPV vaccine, he can consult either a urologist or a gynecologist. Urologists specialize in male reproductive health and can provide appropriate guidance and vaccination. However, gynecologists are typically more focused on female health, so for men, a urologist may be the more relevant choice. It's important to find a healthcare provider who is knowledgeable about HPV and its implications for men.

2. Types of HPV Vaccines: There are currently two main types of HPV vaccines available: the quadrivalent (Gardasil) and the nonavalent (Gardasil 9). The quadrivalent vaccine protects against four HPV types (6, 11, 16, and 18), while the nonavalent vaccine covers nine types (6, 11, 16, 18, 31, 33, 45, 52, and 58). For men, the nonavalent vaccine is generally recommended as it provides broader protection against the types of HPV that can lead to cancers and genital warts. The nonavalent vaccine is particularly beneficial because it covers additional high-risk HPV types that are not included in the quadrivalent vaccine.

3. Age Recommendations for Vaccination: The HPV vaccine is recommended for males aged 9 to 26 years. However, it can be given to individuals up to age 45 based on shared clinical decision-making. The earlier the vaccination is administered, ideally before the onset of sexual activity, the better the protection against HPV-related diseases. There is no upper age limit for vaccination, but the effectiveness may be reduced if given after the onset of sexual activity, as individuals may have already been exposed to some HPV types.

In addition to these points, it's crucial to understand that while the HPV vaccine significantly reduces the risk of HPV-related diseases, it does not eliminate the need for regular health check-ups and screenings. Men should still engage in safe sexual practices, including the use of condoms, to further reduce the risk of HPV transmission and other sexually transmitted infections.

Moreover, it's important to address concerns about vaccine safety. The HPV vaccine has been extensively studied and is considered safe for both men and women. While there have been reports of adverse effects, the overall incidence of serious side effects is very low. The benefits of vaccination in preventing HPV-related cancers and diseases far outweigh the risks.

In conclusion, men should definitely consider getting vaccinated against HPV, and they can consult with a urologist or a healthcare provider knowledgeable about HPV. The nonavalent vaccine is recommended for broader protection, and vaccination is most effective when administered before sexual activity begins. Regular health check-ups and safe sexual practices remain essential components of overall health and well-being.

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