Multiple Neuropathy: Diagnosis and Treatment Insights - Neurology

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Polyneuropathy


My father is 76 years old and has been receiving treatment at Mackay Memorial Hospital's neurology department.
He has undergone brain CT scans and motor nerve reflex tests.
The doctor diagnosed him with radiculitis.
He has been taking medication for about six months, during which he gradually deteriorated from being able to walk to only being able to take a few steps with assistance.
Later, he experienced urinary retention, needing to stand for about ten minutes to urinate a little.
Two months ago, he developed a cough and weakness due to a cold, which led to mucus obstructing his airway and causing hypoxic shock.
He was urgently taken to Zhongxiao Hospital for intubation and gastric tube placement.
The doctors, after hearing the family's explanation of his condition, diagnosed him with polyneuropathy, which is difficult to treat.
He is currently under the care of the thoracic department and relies on a ventilator for survival.

I would like to ask: 1.
Did the doctors at Mackay Memorial Hospital make a misdiagnosis or conceal the condition? 2.
Is the diagnosis from Zhongxiao Hospital correct? I have no other intentions; I just feel that I lack medical knowledge, which may have led to a delay in treatment.
I would appreciate any advice from the doctors.
Thank you.

A Yan, 40~49 year old female. Ask Date: 2000/11/23

Dr. Huang Yingzhe reply Neurology


First, it should be noted that the cause of your father's subsequent hypoxic shock may not necessarily be related to his previous neurological condition.
I wonder on what basis the physician at Chung Hwa Hospital diagnosed him with polyneuropathy? Was it also a neurologist? Furthermore, if there is indeed a correlation, chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) should certainly be considered (both diagnoses include this condition!).
However, it is not the only possible diagnosis.
There are several other conditions that cannot be detailed here and must be evaluated in conjunction with other tests and examinations.

Reply Date: 2000/11/23

More Info


Understanding multiple neuropathy, particularly in the context of your father's condition, requires a nuanced approach to diagnosis and treatment. Multiple neuropathy, or polyneuropathy, refers to a condition where multiple peripheral nerves are damaged, leading to a variety of symptoms such as weakness, numbness, and pain, primarily in the hands and feet. The underlying causes can be diverse, including diabetes, infections, autoimmune diseases, toxins, and hereditary conditions.

In your father's case, the diagnosis of nerve root inflammation suggests a condition known as Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), which is an autoimmune disorder characterized by progressive weakness and impaired sensory function. CIDP can lead to significant disability if not treated effectively. The symptoms you describe, such as the gradual loss of mobility and urinary retention, align with the progression of neuropathy. The fact that he required emergency intervention due to respiratory distress indicates a severe decline in his overall health, which could be related to the underlying neuropathy.

To address your specific questions:
1. Potential Misdiagnosis or Concealment of Information: It is crucial to understand that diagnosing neuropathic conditions can be complex. The initial diagnosis made by the doctors at Mackay Memorial Hospital may not necessarily be incorrect, but it is possible that the full extent of the condition was not initially apparent. Neuropathy can evolve over time, and symptoms may worsen or change, leading to a need for reevaluation. If your father's condition deteriorated significantly after the initial diagnosis, it could indicate that the disease was more aggressive than initially thought or that additional factors contributed to his decline. It is essential to maintain open communication with healthcare providers and seek clarification on any concerns regarding the diagnosis and treatment plan.

2. Correctness of the Diagnosis at Zhongxiao Hospital: The diagnosis of multiple neuropathy at Zhongxiao Hospital seems to align with the symptoms and progression you described. The fact that he is now reliant on a ventilator suggests a severe compromise in respiratory function, which can occur in advanced cases of neuropathy affecting the muscles involved in breathing. It is important to note that multiple neuropathy can lead to complications that may not have been evident during earlier evaluations. The transition to a respiratory care unit indicates that the medical team is taking appropriate steps to manage his critical condition.

In terms of treatment, polyneuropathy management often involves addressing the underlying cause, if known, and may include immunotherapy, physical therapy, and supportive care. In cases like CIDP, corticosteroids or other immunosuppressive agents may be used to reduce inflammation and improve nerve function. Rehabilitation services can also play a crucial role in helping patients regain strength and mobility.

Given the complexity of your father's condition, it may be beneficial to seek a second opinion from a neurologist who specializes in neuropathies. They can provide a comprehensive evaluation and potentially recommend additional diagnostic tests, such as nerve conduction studies or a lumbar puncture, to better understand the underlying pathology.

In conclusion, navigating the diagnosis and treatment of multiple neuropathy requires careful consideration of the patient's evolving symptoms and a collaborative approach with healthcare providers. It is essential to advocate for your father's health and ensure that he receives the most appropriate and effective care possible.

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