Blood Test Abnormalities: When to See a Doctor - Family Medicine

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Blood disorders


Hello, I have been taking the following two medications for acne treatment for about seven months: 1.
Doxycycline 100mg 2.
Aldactone 25mg.
After stopping the medication for 2-3 weeks, I recently had a blood test during a company health check, and the results showed some abnormalities: 1.
WBC (White Blood Cell count) 3.48 x 10^3/cmm (low) [Normal range: 4-11] 2.
Neutrophils 41.4% (low) [Normal range: 45-75%] 3.
Lymphocytes 50.3% (high) [Normal range: 20-45%].
I have a long-standing issue with low blood pressure, but I do not experience dizziness.
My white blood cell count has been slightly low (3-4) at the edge of the normal range during annual health checks.
I would like to know what this issue might be and which specialist I should consult.
Thank you.

Miss Yang, 30~39 year old female. Ask Date: 2017/09/09

Dr. Liao Yaopan reply Family Medicine


Hello, you can consult a hematologist for further evaluation regarding blood cell tests.
Please note that online consultations do not equate to in-person medical visits and cannot provide accurate diagnoses or treatment recommendations.
Changhua Hospital cares about you.

Reply Date: 2017/09/09

More Info


Based on the blood test results you've provided, there are a few key abnormalities that warrant further investigation. Your white blood cell (WBC) count is low at 3.48 x 10^3/cumm, which falls below the normal range of 4-11 x 10^3/cumm. Additionally, your neutrophil percentage is also low at 41.4%, while your lymphocyte percentage is elevated at 50.3%.

Understanding the Results
1. Low WBC Count: A low WBC count, known as leukopenia, can be caused by various factors, including bone marrow disorders, autoimmune diseases, certain infections, or the effects of medications. Since you have been on doxycycline and aldactone, it's important to consider that these medications can influence blood cell counts. Doxycycline, an antibiotic, is generally not associated with significant blood count changes, but prolonged use can sometimes lead to other complications. Aldactone (spironolactone) is a diuretic that can affect electrolyte balance and may have some impact on blood cell production.

2. Neutrophil Count: Neutrophils are a type of white blood cell essential for fighting off infections. A low percentage of neutrophils (below 45%) can indicate a compromised immune response, making you more susceptible to infections. This could be particularly concerning if you notice any signs of infection, such as fever, chills, or unusual fatigue.

3. Elevated Lymphocytes: An elevated lymphocyte count (above 45%) can be a response to infection, inflammation, or, in some cases, chronic stress or certain types of blood disorders. It is not uncommon for lymphocyte levels to rise in response to viral infections or other immune responses.


Next Steps
Given your history of low blood pressure and the current blood test results, it is advisable to consult with a healthcare provider who specializes in hematology or internal medicine. They can perform a more comprehensive evaluation, which may include:
- Repeat Blood Tests: To confirm the findings and monitor any changes over time.

- Bone Marrow Biopsy: If there are concerns about bone marrow function, this test can provide valuable information about blood cell production.

- Infection Screening: If you have any symptoms of infection, further tests may be necessary to identify the cause.

- Review of Medications: Discussing your current medications with your doctor to determine if they may be contributing to your blood count abnormalities.


When to Seek Immediate Care
You should seek immediate medical attention if you experience any of the following symptoms:
- Fever or chills
- Unusual bruising or bleeding
- Persistent fatigue or weakness
- Signs of infection (e.g., cough, sore throat, urinary symptoms)

Conclusion
In summary, your blood test results indicate some abnormalities that should not be ignored. While they may not indicate a severe condition, they do suggest that further evaluation is necessary to rule out any underlying issues. Consulting with a hematologist or an internal medicine physician will provide you with the best course of action and help you understand the implications of your blood test results in the context of your overall health.

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