Gallbladder Stones: Risks, Symptoms, and Treatment Options - Gastroenterology and Hepatology

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Gallstones


Hello, I was diagnosed with gallstones after giving birth in 2011, although previous health checks before pregnancy did not show any gallstones.
During my pregnancy, I experienced severe morning sickness.
I have been living with gallstones for nearly seven years now and have been regularly monitored at a teaching hospital every six months to a year.
During my most recent follow-up in March 2017, a hepatobiliary surgeon noted that my gallbladder wall has thickened by about 0.25 cm.
He mentioned that the thickening could be due to two possibilities: 1.
Chronic inflammation, or 2.
The gallbladder is contracting.
He suggested that while immediate intervention is not necessary, it would be advisable to remove the gallbladder since I have never experienced biliary colic, although I occasionally feel a bloated sensation under my right rib after meals.
I am hesitant to have my gallbladder removed because I have heard it may increase the risk of colorectal cancer, and there is still a possibility of stones in the bile duct.

I would like to ask:
1.
Does thickening of the gallbladder wall necessitate gallbladder removal?
2.
Does gallbladder removal really increase the risk of colorectal cancer?
3.
Do gallstones truly increase the risk of gallbladder cancer?
Thank you, doctor, for your response!

Sebrina, 40~49 year old female. Ask Date: 2017/09/11

Dr. Chen Shidian reply Gastroenterology and Hepatology


Hello, Miss.
According to the latest concepts, middle-aged individuals with gallstones should consider cholecystectomy, especially those who are symptomatic or frequently travel abroad.
Other cancer risk factors are still under research.
Changhua Hospital cares about your health.
Chen Shidian.

Reply Date: 2017/09/11

More Info


Gallbladder stones, or gallstones, are a common condition that can lead to various symptoms and complications. Understanding the risks, symptoms, and treatment options is crucial for making informed decisions regarding management.

Risks and Symptoms of Gallstones
Gallstones can form due to several factors, including obesity, rapid weight loss, pregnancy, and certain dietary habits. In your case, the development of gallstones after pregnancy may be linked to hormonal changes and the increased cholesterol levels that can occur during this time. Symptoms of gallstones can vary widely; some individuals remain asymptomatic, while others may experience significant discomfort. Common symptoms include:
- Biliary Colic: This is characterized by sudden and intense pain in the upper right abdomen, often occurring after meals, especially fatty ones.

- Nausea and Vomiting: These can accompany the pain, particularly during acute episodes.

- Bloating and Indigestion: Some individuals report a feeling of fullness or bloating after eating, which you mentioned experiencing.

Complications from gallstones can include acute cholecystitis (inflammation of the gallbladder), pancreatitis, and even cholangitis (infection of the bile duct). The risk of these complications increases with the presence of symptoms.


Treatment Options
The management of gallstones can be approached in several ways:
1. Observation: If you are asymptomatic or have mild symptoms, a "watchful waiting" approach may be recommended. Regular follow-ups with imaging studies can help monitor the condition.

2. Medications: There are medications available that can dissolve cholesterol-based gallstones, but they are not effective for pigment stones and require long-term use. The recurrence rate is high once the medication is stopped.

3. Surgery: Cholecystectomy, or gallbladder removal, is the most common treatment for symptomatic gallstones. There are two main types of surgery:
- Laparoscopic Cholecystectomy: A minimally invasive procedure that typically results in quicker recovery and less postoperative pain.

- Open Cholecystectomy: A more invasive procedure that may be necessary in complicated cases.


Addressing Your Concerns
1. Gallbladder Wall Thickening: The thickening of the gallbladder wall can indicate chronic inflammation or other underlying issues. While it does not automatically necessitate surgery, it is a sign that should be monitored closely. If you develop symptoms or if the thickening progresses, surgical intervention may become necessary.

2. Increased Risk of Colorectal Cancer: There is no strong evidence to suggest that gallbladder removal increases the risk of colorectal cancer. However, some studies have indicated that patients without a gallbladder may experience changes in bile acid metabolism, which could theoretically influence colorectal health. It's essential to discuss these concerns with your healthcare provider, who can provide personalized advice based on your health history.

3. Gallstones and Gallbladder Cancer: While the presence of gallstones is a risk factor for gallbladder cancer, the overall incidence is low. Most individuals with gallstones will not develop cancer. However, if you have a history of symptomatic gallstones or other risk factors, your healthcare provider may recommend more frequent monitoring.


Conclusion
Given your history and the current findings, it is advisable to have an open discussion with your healthcare provider about the potential benefits and risks of surgery versus continued observation. If you are experiencing symptoms that interfere with your quality of life, surgical intervention may be warranted. Always consider seeking a second opinion if you feel uncertain about the recommendations provided. Your health and comfort should be the primary focus in managing gallbladder stones.

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