Liver Function Test Results: What Do They Mean for Your Health?

Q: Liver Function Test Results: What Do They Mean for Your Health?

Hello： 1. Get enough rest and avoid staying up too late; if you are overweight, you should manage your weight. 2. You can consult a gastroenterologist, and if necessary, arrange for an abdominal ultrasound at Changhua Hospital to monitor your health. Dr. Tsai

Inquiry about liver function tests?

Height: 182 cm, Weight: 65 kg, Age: 19.
I went to bed at midnight the night before the examination.
The results are as follows:
1.
AST: 54 U/L
2.
ALT: 47 U/L
3.
Serum Creatinine: 0.9 mg/dL
4.
Estimated Glomerular Filtration Rate (eGFR): 115.5 ml/min/1.73 m²
(Urinalysis results)
1.
Urine Creatinine: 22.5 mg/dL
2.
Urine Microalbumin: 20.7 mg/dL
3.
Microalbumin/Creatinine Ratio (U): 92.1
In my previous health check, my GPT was above the normal range by about 10 (SGOT was 36 six months ago).
I would like to ask:
1.
Is there something wrong with my health?
2.
If I need to further examine liver function, what tests should I undergo?

Liu Xiansheng, 10~19 year old female. Ask Date: 2017/09/25

Dr. Cai Anshun reply Gastroenterology and Hepatology

Hello: 1.
Get enough rest and avoid staying up too late; if you are overweight, you should manage your weight.
2.
You can consult a gastroenterologist, and if necessary, arrange for an abdominal ultrasound at Changhua Hospital to monitor your health.
Dr.
Tsai An-shun.

Reply Date: 2017/09/25

More Info

Understanding liver function test results is crucial for assessing your overall health, especially when abnormal values are present. Based on the information you've provided, your liver enzyme levels (AST and ALT) are elevated, which can indicate potential liver issues. Let's break down what these results mean and what steps you should consider taking.

1. Understanding Your Liver Function Test Results
AST (Aspartate Aminotransferase) and ALT (Alanine Aminotransferase) are enzymes found in the liver. They play a role in amino acid metabolism and are released into the bloodstream when liver cells are damaged. Normal ranges for these enzymes can vary slightly between laboratories, but generally, AST is considered normal below 40 U/L, and ALT below 35 U/L. Your results show AST at 54 U/L and ALT at 47 U/L, indicating that both are elevated.

Elevated liver enzymes can be caused by a variety of factors, including:
- Fatty Liver Disease: This is one of the most common causes of elevated liver enzymes, especially in individuals who are overweight or have a sedentary lifestyle.

- Alcohol Consumption: Even though you mentioned that you do not drink regularly, occasional drinking can still impact liver enzyme levels.

- Medications: Certain medications can cause liver enzyme elevations. If you are taking any medications or supplements, it’s worth discussing them with your healthcare provider.

- Viral Hepatitis: Infections such as Hepatitis B or C can lead to elevated liver enzymes.

- Metabolic Disorders: Conditions like diabetes or metabolic syndrome can also affect liver health.

2. Next Steps for Further Evaluation
Given your elevated liver enzymes, it is advisable to conduct further testing to determine the underlying cause. Here are some recommended tests:
- Repeat Liver Function Tests: This will help confirm whether the elevation is persistent.

- Hepatitis Panel: Testing for Hepatitis A, B, and C can rule out viral infections as a cause of liver enzyme elevation.

- Ultrasound of the Liver: This imaging test can help identify fatty liver disease, liver lesions, or other structural abnormalities.

- Additional Blood Tests: Tests for autoimmune liver diseases, iron studies, and metabolic panels can provide more insight into your liver health.

3. Lifestyle Modifications
While awaiting further testing, consider implementing some lifestyle changes that can support liver health:
- Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid high-fat, sugary, and processed foods.

- Exercise: Regular physical activity can help reduce liver fat and improve overall health. Aim for at least 150 minutes of moderate-intensity exercise per week.

- Hydration: Drink plenty of water to help your liver function optimally.

- Limit Alcohol: Since alcohol can exacerbate liver issues, it’s wise to limit or avoid it altogether.

4. Monitoring and Follow-Up
It’s essential to have regular follow-ups with your healthcare provider to monitor your liver function and any changes in your health status. Depending on the results of further tests, your doctor may recommend specific treatments or lifestyle changes tailored to your condition.

Conclusion
In summary, your elevated liver enzymes indicate that further investigation is warranted to determine the cause. By taking proactive steps in terms of testing and lifestyle modifications, you can significantly impact your liver health and overall well-being. Always consult with your healthcare provider for personalized advice and treatment options based on your specific situation.

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