Your Liver Function Test Results: What They Mean for You

Q: Your Liver Function Test Results: What They Mean for You

Hello： <br>1. <br>A positive surface antigen (HBsAg positive) indicates the presence of the hepatitis B virus in the body, meaning you are a carrier of hepatitis B. <br>If you recover, you will develop hepatitis B antibodies, resulting in a positive HBsAb and a negative HBsAg. <b

Liver function index issues?

Hello Doctor: Today I received the test report from the Foundation for Liver Cancer Prevention and Treatment, and the results are as follows: Hepatitis B surface antigen: + Hepatitis B surface antibody: + Hepatitis C antibody: - AST (GOT): 36 ALT (GPT): 48 AFP: 1.9 I have had a long-term habit of staying up late (insufficient sleep) and smoking for about 10 years, along with a busy work schedule and high stress, so I have always suspected there might be an issue with my liver.
After seeing the report results today, I was quite shocked and also looked at related comments and responses on the website, but I still feel anxious.
I kindly ask the doctor to explain my test report and what steps I should take.
Additionally, what is the highest level that liver function indices can reach? In your response, you mentioned that liver function indices can fluctuate; does my level count as severe? Thank you for your attentive response!

Xiao Xing, 20~29 year old female. Ask Date: 2006/05/05

Dr. Lin Minghui reply Gastroenterology and Hepatology

Hello:
1.
A positive surface antigen (HBsAg positive) indicates the presence of the hepatitis B virus in the body, meaning you are a carrier of hepatitis B.
If you recover, you will develop hepatitis B antibodies, resulting in a positive HBsAb and a negative HBsAg.
It is recommended that you continue to be monitored as a hepatitis B carrier and have regular follow-ups on liver function.
2.
Your liver enzyme level (GPT) is 48, which is 1 to 2 times the normal range.
This is not very severe, but it requires monitoring for serious liver necrosis, as GOT and GPT can reach several thousand, accompanied by jaundice and anorexia symptoms.
For chronic hepatitis B patients, if GPT remains above 2 times the normal level for an extended period, antiviral therapy may be considered.
In patients with liver cirrhosis, GPT levels are mostly between 1 to 2 times the normal range or normal.
3.
It is advisable to regularly monitor liver function and undergo abdominal ultrasound.
Methods to protect the liver include avoiding unnecessary medications, maintaining a regular lifestyle, abstaining from alcohol, and ensuring a balanced diet.
Sincerely, Dr.
Lin Ming-Hui, Internal Medicine.

Reply Date: 2006/05/05

More Info

Understanding your liver function test results is crucial, especially when you have a history of lifestyle factors that can impact liver health, such as insufficient sleep, smoking, and high stress. Let's break down your test results and what they mean for you.

Test Results Breakdown:
1. Hepatitis B Surface Antigen (HBsAg): Positive
- This indicates that you are currently infected with the Hepatitis B virus. It is essential to monitor this condition closely, as chronic Hepatitis B can lead to liver damage over time.

2. Hepatitis B Surface Antibody (Anti-HBs): Positive
- The presence of this antibody suggests that your immune system has responded to the Hepatitis B virus, either from a past infection or vaccination. However, in your case, the simultaneous positivity of HBsAg and Anti-HBs is unusual and warrants further investigation.

3. Hepatitis C Antibody (Anti-HCV): Negative
- This result indicates that you do not have a current or past infection with Hepatitis C, which is a positive finding.

4. AST (GOT): 36
- This value is within the normal range (typically 10-40 U/L), indicating that there is no significant liver cell damage at this moment.

5. ALT (GPT): 48
- This value is slightly elevated, as normal ranges are generally up to 40 U/L. Elevated ALT levels can indicate liver inflammation or damage, often associated with conditions like fatty liver disease, viral hepatitis, or alcohol-related liver disease.

6. Alpha-fetoprotein (AFP): 1.9
- This is a tumor marker that can be elevated in liver cancer or severe liver disease. Your result is within the normal range, which is reassuring.

Interpretation and Recommendations:
Given your results, particularly the positive HBsAg and slightly elevated ALT, it is crucial to follow up with a healthcare provider specializing in liver diseases, such as a gastroenterologist or hepatologist. They may recommend additional tests, including:
- Hepatitis B Viral Load (HBV DNA): To determine the amount of virus in your blood.

- Liver Function Tests: To monitor your liver enzymes over time.

- Liver Ultrasound: To assess the liver's structure and check for any abnormalities.

Lifestyle Modifications:
Your lifestyle factors, such as smoking, lack of sleep, and high stress, can significantly impact liver health. Here are some recommendations:
1. Quit Smoking: Smoking can exacerbate liver damage and overall health. Consider seeking support to quit.

2. Improve Sleep Hygiene: Aim for 7-9 hours of quality sleep per night. Establish a regular sleep schedule and create a restful environment.

3. Manage Stress: Engage in stress-reducing activities such as yoga, meditation, or regular exercise.

4. Limit Alcohol Consumption: Given your liver function results, it would be wise to limit or eliminate alcohol intake, as it can further stress the liver.

5. Healthy Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Avoid processed foods and excessive sugars.

Monitoring and Follow-Up:
Liver function tests can fluctuate due to various factors, including diet, exercise, and overall health. While your current ALT level is slightly elevated, it is not necessarily indicative of severe liver disease. However, continuous monitoring is essential, especially with your Hepatitis B status.
In conclusion, while your results show some areas of concern, particularly with the Hepatitis B infection and elevated ALT, proactive management through lifestyle changes and regular medical follow-up can significantly improve your liver health. Always consult with your healthcare provider for personalized advice and treatment options.

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