Rheumatoid Arthritis and Uric Acid Levels in Blood Tests - Internal Medicine

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Rheumatoid arthritis and uric acid?


Hello! I would like to ask if the rheumatoid factor test report includes uric acid levels.
I checked my report yesterday, and there was no rheumatoid factor, but the inflammatory markers were elevated.
I am concerned that even without rheumatoid factor, I might have high uric acid levels.
The doctor asked about my family history of rheumatoid arthritis, and I said there was none, but they did not inquire about my family's history of gout.
My father and brother have gout, and I am unsure if I might have elevated uric acid levels.
So, I want to know if the rheumatoid factor test report includes uric acid levels.
If it does, and the doctor did not mention gout, does that mean I do not have a problem with uric acid and gout? Is it just simple arthritis?

Xiao Ya, 20~29 year old female. Ask Date: 2017/10/25

Dr. Gao Jiankai reply Internal Medicine


Hello, thank you for your inquiry.
The rheumatoid factor and uric acid levels are two different tests.
Therefore, if your physician did not include these two tests in the examination items, you may not receive results for either the rheumatoid factor or uric acid levels.
It would be advisable to ask your physician whether the tests for "rheumatoid factor" or "uric acid levels" were ordered.
If they were, inquire whether there are any abnormalities; if there are abnormalities, further ask about the implications of those "abnormalities" for a more accurate response from your physician.
The Allergy, Immunology, and Rheumatology Department of Changhua Hospital, Ministry of Health and Welfare, cares about you.

Reply Date: 2017/10/25

More Info


Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder that primarily affects the joints but can also have systemic effects. When interpreting blood test results for RA, several key markers are typically evaluated, including rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA), and inflammatory markers such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). However, uric acid levels are not standard components of RA testing, as they are more closely associated with gout, a different type of inflammatory arthritis.

In your case, you mentioned that your blood test report did not include rheumatoid factor but indicated elevated inflammatory markers. This suggests that while you may not have RA, there is still an underlying inflammatory process occurring in your body. The absence of rheumatoid factor does not rule out other forms of arthritis or inflammatory conditions. It is essential to consider your family history of gout, as elevated uric acid levels can lead to gout attacks, characterized by sudden and severe joint pain, often in the big toe.

Uric acid is a waste product formed from the breakdown of purines, substances found in many foods and drinks. When uric acid levels become too high, it can crystallize in the joints, leading to inflammation and pain associated with gout. Given your family history of gout, it would be prudent to monitor your uric acid levels, especially if you experience symptoms such as joint pain or swelling.

To answer your question directly: standard rheumatoid arthritis blood tests do not typically include uric acid levels. If your doctor did not specifically order a uric acid test, it may not have been evaluated in your recent blood work. If you are concerned about the possibility of gout or elevated uric acid levels, it would be advisable to discuss this with your healthcare provider. They can order specific tests to measure your uric acid levels and assess whether they are within a normal range.

Additionally, it is important to note that having a family history of gout increases your risk of developing elevated uric acid levels. Lifestyle factors, such as diet and hydration, can also influence uric acid levels. Foods high in purines, such as red meat, shellfish, and sugary beverages, can contribute to increased uric acid production. Staying well-hydrated and maintaining a balanced diet may help manage uric acid levels.

In summary, while your blood test for rheumatoid arthritis may not include uric acid levels, it is essential to consider your family history and any symptoms you may be experiencing. If you have concerns about gout or elevated uric acid levels, it is advisable to speak with your healthcare provider for further evaluation and management. They can help you determine the appropriate tests and develop a plan to address any underlying issues related to inflammation or uric acid levels.

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