Hypothyroidism: Should You Take Medication or Seek Further Testing? - Internal Medicine

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Hypothyroidism issues?


Hello Doctor, I am currently undergoing infertility treatment, so I need to check if there are any issues with my thyroid.
Hospital A tested and found that I have hypothyroidism, with a TSH level of 7.026 (the standard range is 0.35-5.5).
They prescribed ELTROXIN 0.05 for me.
However, I have had annual blood tests for my thyroid, and everything was normal (I was tested in August this year, and all results were normal).
Therefore, I went back to Hospital B, where I originally had my thyroid checked, and the results were normal with a TSH level of 2.537 (the standard range is 0.4-4.0).
The doctor at Hospital B mentioned that the reagents used at Hospital A are different (due to different standards), and that my results from Hospital A should not warrant medication.
Since my results from Hospital B are normal, he does not recommend that I take medication (fearing that my body may not produce sufficient hormones on its own in the future).

My questions are:
1) Should I take the medication? (If I do take it, I might only take it every 2-3 days because I am concerned about taking medication when I do not have a condition.)
2) Do I need to get a third opinion from another hospital? Thank you.

Xiao Gua, 40~49 year old female. Ask Date: 2017/12/06

Dr. Xiao Yongxun reply Internal Medicine


Dear Miss Xiao Gua:
1.
Personally, I am unsure how to answer your question.

2.
I can only tell you that, according to general medical principles, hypothyroidism is characterized by decreased levels of T3 (triiodothyronine), decreased levels of T4 (thyroxine), and increased levels of TSH (thyroid-stimulating hormone).
The causes of hypothyroidism include congenital cretinism, iodine deficiency, thyroidectomy or radiation therapy, Hashimoto's thyroiditis, autoimmune diseases, and thyroid hormone resistance, among others.
Therefore, further examination and analysis are necessary to determine the true cause.
However, it is indeed true that hypothyroidism can lead to endocrine or menstrual irregularities and even result in infertility.

3.
In cases where you encounter differing opinions from physicians or suspected controversies, I believe it may be beneficial to discuss this with relevant specialists or consult an endocrinologist for differential diagnosis to find a more suitable approach that you can accept.

Reply Date: 2017/12/06

More Info


Hypothyroidism, or an underactive thyroid, is a condition where the thyroid gland does not produce enough thyroid hormones, which are crucial for regulating metabolism, energy levels, and overall bodily functions. Your situation, where you have received conflicting test results regarding your thyroid function, raises important questions about the need for medication and further testing.

1. Understanding Your Test Results:
- The TSH (Thyroid Stimulating Hormone) level is a key indicator of thyroid function. A TSH level of 7.026 mIU/L, as reported by Hospital A, indicates hypothyroidism since it is above the normal range (0.35-5.5 mIU/L). This would typically warrant treatment with levothyroxine (Eltroxin) to normalize thyroid hormone levels.

- Conversely, the TSH level of 2.537 mIU/L from Hospital B falls within the normal range (0.4-4.0 mIU/L), suggesting that your thyroid function is adequate at that time.

2. Medication Considerations:
- If you are diagnosed with hypothyroidism, the standard treatment is to take thyroid hormone replacement therapy, such as Eltroxin. However, the decision to start medication should be based on consistent test results and clinical symptoms. If you are asymptomatic and your TSH levels are normal in the second test, it may not be necessary to start medication.

- It is important to note that taking thyroid medication when it is not needed can lead to adverse effects, including symptoms of hyperthyroidism (overactive thyroid), such as anxiety, weight loss, and heart palpitations. Therefore, your concern about taking medication unnecessarily is valid.

3. Further Testing:
- Given the discrepancies in your test results, it may be prudent to seek a third opinion or further testing. This could involve retesting your TSH and free T4 levels at a different laboratory to confirm the diagnosis. It is also beneficial to ensure that the same testing methods and reference ranges are used for consistency.

- Additionally, consider discussing the possibility of testing for thyroid antibodies (such as anti-TPO antibodies) to determine if there is an autoimmune component, like Hashimoto's thyroiditis, which is a common cause of hypothyroidism.

4. Monitoring and Follow-Up:
- If you decide to start medication, regular follow-up and monitoring of your TSH levels are essential to ensure that the dosage is appropriate and to avoid potential side effects. Typically, TSH levels are checked every 6-12 months once stable.

- If you choose not to take medication based on the normal results from Hospital B, it is still important to monitor your thyroid function regularly, especially since you are undergoing fertility treatments, as thyroid health can impact reproductive health.

In conclusion, the decision to take medication for hypothyroidism should be based on consistent test results and clinical evaluation. If there is uncertainty, seeking a third opinion or further testing is a reasonable approach. Always discuss your concerns and treatment options with your healthcare provider to make an informed decision that aligns with your health goals.

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