Chronic Leg Pain: Seeking Solutions for Vascular and Nerve Issues - Cardiology

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Foot pain issues?


Hello Doctor, my mother is 63 years old and has been suffering from foot pain for many years.
She has seen specialists in neurology, orthopedics, rehabilitation, vascular surgery, and dermatology, and has tried various medications.
She has also undergone balloon angioplasty twice, but despite being told there was a blockage, there has been no improvement.

Currently, her symptoms include severe swelling in both feet, cramping pain (she has experienced sensations like burning and stabbing), unexplained sores, and recently, darkening of the skin.
The affected areas range from the soles of her feet to her calves, and she cannot wear closed shoes due to pain in her heels and ankles.
Each toe is swollen.

She has previously been diagnosed with venous compression syndrome and sympathetic neuropathy.
Although she continues to take medication, it has not alleviated her pain, and it is unclear if the change in seasons is contributing to her condition.
The pain has become more pronounced, and the sores seem to be enlarging.

Doctors have advised her to keep her legs elevated, but the sores and darkening of the skin have made her very uncomfortable and anxious.
We hope to find a doctor who can help us understand what is happening.
We are unsure which specialist to consult next.

Amy Wu, 20~29 year old female. Ask Date: 2017/12/09

Dr. He Dongjin reply Cardiology


Hello, I apologize for not being able to see the patient in person.
Without a direct examination, I cannot provide you with more accurate advice.
I recommend discussing the next treatment strategy with your attending physician.
Take care, Changhua Hospital is concerned about you.

Reply Date: 2017/12/09

More Info


Chronic leg pain, especially in the context of vascular and nerve issues, can be a complex and multifaceted problem, particularly in a 63-year-old patient like your mother. Given her extensive medical history and the various specialists she has consulted, it is crucial to consider both vascular and neurological components in her symptoms.

From your description, your mother is experiencing severe swelling, burning pain, and unusual skin changes, including darkening and the presence of unexplained holes. These symptoms could be indicative of several underlying conditions, including chronic venous insufficiency, peripheral artery disease, or even complex regional pain syndrome (CRPS).
Chronic Venous Insufficiency (CVI): This condition occurs when the veins in the legs are unable to pump enough blood back to the heart, leading to pooling of blood in the legs. Symptoms often include swelling, pain, and skin changes such as discoloration or ulceration. The fact that your mother has undergone balloon angioplasty suggests that there may have been some vascular obstruction, which could contribute to CVI.
Peripheral Artery Disease (PAD): This is another vascular condition that results from narrowed arteries reducing blood flow to the limbs. Symptoms can include leg pain during activity (claudication), numbness, and changes in skin color. The burning and stabbing sensations your mother experiences could be related to inadequate blood flow to the nerves in her legs.

Complex Regional Pain Syndrome (CRPS): This is a chronic pain condition that usually affects a limb after an injury. It is characterized by severe pain, swelling, and changes in skin color and temperature. The symptoms can be disproportionate to the initial injury and can lead to significant disability.

Sympathetic Nervous System Dysfunction: The diagnosis of sympathetic nerve dysfunction or dysautonomia could also explain some of her symptoms. This condition can lead to abnormal blood flow regulation and pain perception, contributing to the burning and stabbing sensations.

Given the complexity of her symptoms and the lack of improvement with current treatments, it may be beneficial to consider a multidisciplinary approach. Here are some potential next steps:
1. Re-evaluation by a Vascular Specialist: Since your mother has already undergone balloon angioplasty, a follow-up with a vascular surgeon may be necessary to assess the current state of her vascular health. Additional imaging studies, such as Doppler ultrasound, could provide insights into blood flow and venous function.

2. Consultation with a Pain Management Specialist: A pain management clinic can offer a comprehensive approach to chronic pain, including medication management, physical therapy, and interventional procedures such as nerve blocks or spinal cord stimulation.

3. Physical Therapy: A tailored physical therapy program focusing on strengthening and improving circulation in the legs may help alleviate some symptoms. Techniques such as compression therapy could also be beneficial for managing swelling.

4. Dermatological Evaluation: Given the skin changes, a consultation with a dermatologist may be warranted to assess the lesions and determine if they are related to vascular issues or another dermatological condition.

5. Neurological Assessment: If not already done, a thorough neurological evaluation, including nerve conduction studies and electromyography (EMG), could help identify any nerve damage or dysfunction contributing to her symptoms.

6. Lifestyle Modifications: Encouraging your mother to elevate her legs regularly, engage in gentle exercises, and maintain a healthy diet can also support vascular health.

In conclusion, your mother's condition requires a comprehensive and coordinated approach involving multiple specialties. It is essential to communicate openly with her healthcare providers about her symptoms and the lack of improvement with current treatments. This will help ensure that she receives the most appropriate and effective care tailored to her specific needs.

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