Switching from Qlaira to Diane: Is It Safe and Effective? - Obstetrics and Gynecology

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Qilian is changed to Dalian?


I would like to ask the doctor if I can switch from taking Qlaira to taking Diane, since the pharmacy near my new home only sells Diane.
Will the contraceptive effect be the same? I took one pill yesterday; is it still possible to switch back to Qlaira? (I took Diane for a while a few years ago without any adverse reactions.)

Xiao Ying, 20~29 year old female. Ask Date: 2018/01/12

Dr. Huang Jianzhong reply Obstetrics and Gynecology


I have been taking Qlaira, but the pharmacy near my new home only sells Diane.
Can I switch to taking Diane? Answer: Yes, is the contraceptive effect the same? Answer: I took one yesterday; is it still possible to switch back to Qlaira? (I took Diane for a while a few years ago without any adverse reactions.) Answer: Yes, it is still possible.

Reply Date: 2018/01/12

More Info


Switching from one oral contraceptive to another, such as from Qlaira to Diane, is a common concern for many women. Both Qlaira and Diane are combined oral contraceptives, but they contain different active ingredients and have different dosing regimens. Qlaira contains estradiol valerate and dienogest, while Diane contains ethinylestradiol and cyproterone acetate.
When considering a switch, it is essential to understand that while both medications are effective for contraception, their hormonal compositions and potential side effects may differ. Qlaira is a unique formulation that mimics the natural menstrual cycle more closely due to its varying hormone levels throughout the cycle. Diane, on the other hand, is often prescribed not only for contraception but also for its anti-androgenic properties, which can help with conditions like acne or hirsutism.

In terms of safety, switching from Qlaira to Diane is generally considered safe, especially since you have previously taken Diane without any adverse reactions. However, it is crucial to ensure that you do not have any contraindications for taking Diane, such as a history of blood clots, certain cancers, or liver disease.
Regarding effectiveness, both contraceptives are effective when taken correctly. However, it is important to note that when switching from one oral contraceptive to another, there may be a short period during which you are not fully protected against pregnancy. If you have already taken one pill of Diane, you should continue taking it as directed. If you switch back to Qlaira, it is advisable to use an additional form of contraception, such as condoms, for at least seven days after the switch to ensure you are adequately protected.

If you are considering switching back to Qlaira after taking Diane for a short period, it is typically safe to do so. However, you should consult with your healthcare provider to discuss your specific situation, including any side effects you may have experienced and your overall health history. They can provide personalized advice and ensure that you are making the best choice for your contraceptive needs.

In summary, switching from Qlaira to Diane is generally safe and effective, especially since you have a history of tolerating Diane well. Just be mindful of the potential need for additional contraceptive measures during the transition period and consult with your healthcare provider for tailored guidance.

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